Genome Property Definition Page
Accession | GenProp0797 | |
Name | selenocysteinyl-tRNA, PSTK/SepSecS pathway | |
Type | PATHWAY | |
Description | This pathway is the archaeal and eukaryotic system for converting the serine on selenocysteine-tRNA to selenocysteine. This first enzyme is a kinase, L-seryl-tRNA(Sec) kinase (PSTK). The second is Sep-tRNA:Sec-tRNA synthase (SepSecS). In bacteria, this two-enzyme pathway is replaced by SelA (TIGR00474). | |
JCVI Role | tRNA aminoacylation | |
Parent Property | GenProp0126: amino acid biosynthesis | |
Literature References |
| |
Gene Ontology Term | GO:0016260: selenocysteine biosynthetic process (biological_process) |
Components
Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
---|---|---|---|---|
L-seryl-tRNA(Sec) kinase | pstK | YES | TIGR03574 (HMM): L-seryl-tRNA(Sec) kinase | GO:0016260: selenocysteine biosynthetic process |
O-phosphoseryl-tRNA(Sec) selenium transferase | spcS | YES | TIGR03531 (HMM): O-phosphoseryl-tRNA(Sec) selenium transferase | GO:0016260: selenocysteine biosynthetic process |
Parent Properties
Accession | Name |
---|---|
GenProp0126 | amino acid biosynthesis |
Sibling Properties
Accession | Name |
---|---|
GenProp0001 | chorismate biosynthesis via shikimate |
GenProp0016 | selenocysteine system |
GenProp0037 | tryptophan biosynthesis from ribose-5-phosphate |
GenProp0039 | phenylalanine biosynthesis from chorismate |
GenProp0045 | tyrosine biosynthesis from chorismate |
GenProp0087 | arginine biosynthesis from glutatmate via N-acetylglutamate |
GenProp0109 | histidine biosynthesis from ribose-5-phosphate |
GenProp0111 | proline biosynthesis from glutamate |
GenProp0117 | arginine biosynthesis from ornithine, carbamoyl-p and aspartate |
GenProp0118 | ornithine biosynthesis from glutamate, acetylated branch |
GenProp0159 | threonine biosynthesis from aspartate semialdehyde |
GenProp0160 | aspartate semialdehyde biosynthesis from aspartate |
GenProp0161 | methionine biosynthesis from homoserine |
GenProp0162 | isoleucine biosynthesis from threonine and pyruvate |
GenProp0163 | valine biosynthesis from pyruvate |
GenProp0164 | leucine biosynthesis from pyruvate and acetyl-CoA |
GenProp0178 | glycine cleavage system |
GenProp0199 | lysine biosynthesis |
GenProp0304 | cysteine biosynthesis, tRNA-dependent |
GenProp0305 | cysteine biosynthesis |
GenProp0729 | methionine salvage from methylthioadenosine |