Genome Property Definition Page

Nameglycine cleavage system
DescriptionThree distinctive components of the glycine cleavage enzyme are the P protein, H protein, and T protein. Dihydrolipoamide dehydrogenase may be a part of a number of different enzyme contexts, and is the L protein of the glycine cleavage system.
JCVI RoleAmino acids and amines
Parent PropertyGenProp0126: amino acid biosynthesis
Web ReferencesIUBMB: Glycine Cleavage System
KEGG: Glycine, serine and threonine metabolism
Gene Ontology TermGO:0006546: glycine catabolic process (biological_process)

Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
glycine cleavage system H proteingcvHYESTIGR00527 (HMM): glycine cleavage system H proteinGO:0006546: glycine catabolic process
dihydrolipoamide dehydrogenasegcvLYESTIGR01350 (HMM): dihydrolipoyl dehydrogenase
glycine cleavage system P proteingcvPYESPF02347 (HMM): glycine cleavage system P-proteinGO:0006546: glycine catabolic process
glycine cleavage system T proteingcvTYESTIGR00528 (HMM): glycine cleavage system T proteinGO:0006546: glycine catabolic process

Parent Properties
GenProp0126amino acid biosynthesis

Sibling Properties
GenProp0001chorismate biosynthesis via shikimate
GenProp0016selenocysteine system
GenProp0037tryptophan biosynthesis from ribose-5-phosphate
GenProp0039phenylalanine biosynthesis from chorismate
GenProp0045tyrosine biosynthesis from chorismate
GenProp0087arginine biosynthesis from glutatmate via N-acetylglutamate
GenProp0109histidine biosynthesis from ribose-5-phosphate
GenProp0111proline biosynthesis from glutamate
GenProp0117arginine biosynthesis from ornithine, carbamoyl-p and aspartate
GenProp0118ornithine biosynthesis from glutamate, acetylated branch
GenProp0159threonine biosynthesis from aspartate semialdehyde
GenProp0160aspartate semialdehyde biosynthesis from aspartate
GenProp0161methionine biosynthesis from homoserine
GenProp0162isoleucine biosynthesis from threonine and pyruvate
GenProp0163valine biosynthesis from pyruvate
GenProp0164leucine biosynthesis from pyruvate and acetyl-CoA
GenProp0199lysine biosynthesis
GenProp0304cysteine biosynthesis, tRNA-dependent
GenProp0305cysteine biosynthesis
GenProp0729methionine salvage from methylthioadenosine
GenProp0797selenocysteinyl-tRNA, PSTK/SepSecS pathway