Genome Property Definition Page
| Accession | GenProp0178 |
| Name | glycine cleavage system |
| Type | SYSTEM |
| Description | Three distinctive components of the glycine cleavage enzyme are the P protein, H protein, and T protein. Dihydrolipoamide dehydrogenase may be a part of a number of different enzyme contexts, and is the L protein of the glycine cleavage system. |
| JCVI Role | Amino acids and amines |
| Parent Property | GenProp0126: amino acid biosynthesis |
| Web References | IUBMB: Glycine Cleavage System KEGG: Glycine, serine and threonine metabolism |
| Gene Ontology Term | GO:0006546: glycine catabolic process (biological_process) |
Components
| Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
|---|---|---|---|---|
| glycine cleavage system H protein | gcvH | YES | TIGR00527 (HMM): glycine cleavage system H protein | GO:0006546: glycine catabolic process |
| dihydrolipoamide dehydrogenase | gcvL | YES | TIGR01350 (HMM): dihydrolipoyl dehydrogenase | |
| glycine cleavage system P protein | gcvP | YES | PF02347 (HMM): glycine cleavage system P-protein | GO:0006546: glycine catabolic process |
| glycine cleavage system T protein | gcvT | YES | TIGR00528 (HMM): glycine cleavage system T protein | GO:0006546: glycine catabolic process |
Parent Properties
| Accession | Name |
|---|---|
| GenProp0126 | amino acid biosynthesis |
Sibling Properties
| Accession | Name |
|---|---|
| GenProp0001 | chorismate biosynthesis via shikimate |
| GenProp0016 | selenocysteine system |
| GenProp0037 | tryptophan biosynthesis from ribose-5-phosphate |
| GenProp0039 | phenylalanine biosynthesis from chorismate |
| GenProp0045 | tyrosine biosynthesis from chorismate |
| GenProp0087 | arginine biosynthesis from glutatmate via N-acetylglutamate |
| GenProp0109 | histidine biosynthesis from ribose-5-phosphate |
| GenProp0111 | proline biosynthesis from glutamate |
| GenProp0117 | arginine biosynthesis from ornithine, carbamoyl-p and aspartate |
| GenProp0118 | ornithine biosynthesis from glutamate, acetylated branch |
| GenProp0159 | threonine biosynthesis from aspartate semialdehyde |
| GenProp0160 | aspartate semialdehyde biosynthesis from aspartate |
| GenProp0161 | methionine biosynthesis from homoserine |
| GenProp0162 | isoleucine biosynthesis from threonine and pyruvate |
| GenProp0163 | valine biosynthesis from pyruvate |
| GenProp0164 | leucine biosynthesis from pyruvate and acetyl-CoA |
| GenProp0199 | lysine biosynthesis |
| GenProp0304 | cysteine biosynthesis, tRNA-dependent |
| GenProp0305 | cysteine biosynthesis |
| GenProp0729 | methionine salvage from methylthioadenosine |
| GenProp0797 | selenocysteinyl-tRNA, PSTK/SepSecS pathway |