Genome Property Definition Page

Namequinohemoprotein amine dehydrogenase
DescriptionThis system is characterized by three subunits of the mature enzyme, plus one radical SAM protein involved in modification of the gamma subunit. The gamma subunit contains two unusual modifications. One is a cysteine tryptophylquinone, which unlike PQQ is derived from the polypeptide precursor. The other is intrapeptidyl thioether cross-linking.
Parent PropertyGenProp0142: catabolism
Literature References
[ 1 ]Ono K, Okajima T, Tani M, Kuroda S, Sun D, Davidson VL, Tanizawa K  Involvement of a putative [Fe-S]-cluster-binding protein in the biogenesis of quinohemoprotein amine dehydrogenase.  J Biol Chem. 2006 May 12;281(19):13672-84.  PMID 16546999
[ 2 ]Satoh A, Kim JK, Miyahara I, Devreese B, Vandenberghe I, Hacisalihoglu A, Okajima T, Kuroda S, Adachi O, Duine JA, Van Beeumen J, Tanizawa K, Hirotsu K  Crystal structure of quinohemoprotein amine dehydrogenase from Pseudomonas putida. Identification of a novel quinone cofactor encaged by multiple thioether cross-bridges.  J Biol Chem. 2002 Jan 25;277(4):2830-4.  PMID 11704672
Gene Ontology TermGO:0030058: amine dehydrogenase activity (molecular_function)
GO:0043687: post-translational protein modification (biological_process)

Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
quinohemoprotein amine dehydrogenase maturation proteinQH_SAMYESTIGR03906 (HMM): quinohemoprotein amine dehydrogenase maturation proteinGO:0043687: post-translational protein modification
quinohemoprotein amine dehydrogenase, alpha subunitQH_alpYESTIGR03908 (HMM): quinohemoprotein amine dehydrogenase, alpha subunitGO:0030058: amine dehydrogenase activity
quinohemoprotein amine dehydrogenase, beta subunitQH_betYESTIGR03907 (HMM): quinohemoprotein amine dehydrogenase, beta subunitGO:0030058: amine dehydrogenase activity
quinohemoprotein amine dehydrogenase, gamma subunitQH_gamYESPF08992 (HMM): quinohemoprotein amine dehydrogenase, gamma subunitGO:0030058: amine dehydrogenase activity

Parent Properties

Sibling Properties
GenProp0055polyhydroxyalkanoic acids
GenProp0141galactose-6-phosphate degradation via tagatose-6-phosphate
GenProp0156cyanophycin-like storage polymers
GenProp0168glycogen system
GenProp0210phenylacetic acid catabolism
GenProp02314-hydroxyphenylacetate degradation
GenProp0233GABA utilization
GenProp02382-aminoethylphosphonate catabolism to acetaldehyde
GenProp0239propionyl-CoA catabolism
GenProp0241phosphonate catabolism
GenProp0271trehalose utilization
GenProp0272pyruvate fermentation to acetoin
GenProp0273protocatechuate degradation to beta-ketoadipate
GenProp0283beta-ketoadipate degradation to succinyl-CoA and acetyl-CoA
GenProp0294ethanolamine degradation proteinaceous organelle
GenProp0457rhamnose catabolism
GenProp0458fucose catabolism
GenProp0461utilization of deoxynucleosides
GenProp0653ectoine catabolism
GenProp0674malonate decarboxylase
GenProp0686allantoin catabolism to glyoxalate and urea
GenProp0687allantoin catabolism to oxamate and carbamoyl-phosphate
GenProp0688urate catabolism to allantoin
GenProp0693fructose utilization as fructose-1,6-bisphosphate
GenProp0694glucose utilization as fructose-1,6-bisphosphate
GenProp0700purine catabolism via urate, xanthine and allantoin
GenProp0702benzoyl-CoA reductase
GenProp07034-hydroxybenzoyl-CoA reductase
GenProp0706cyclohexa-1,5-diene-1-carbonyl-CoA to 3-hydroxypimelyl-CoA, dch/had/oah pathway
GenProp0708catechol meta-cleavage pathway
GenProp0709benzoate catabolism BoxABC pathway
GenProp0711catechol ortho-cleavage upper pathway
GenProp0714galactarate utilization via tartronate semi-aldehyde
GenProp0715galactarate utilization via 2-oxoglutarate semialdehyde
GenProp0716glucarate utilization via tartronate semi-aldehyde
GenProp0717glucarate utilization via 2-oxoglutarate semialdehyde
GenProp0718oxalate degradation
GenProp0734amino acid catabolism
GenProp0749choline sulfate utilization
GenProp0760putrescine degradation to GABA via gamma-glutamylation
GenProp0763nicotinate fermentation to pyruvate and propionate
GenProp0810encapsulin proteinaceous organelle
GenProp0813pyrimidine utilization operon, RutABCDEFGR
GenProp1071myo-inositol catabolism
GenProp1072cyanase system
GenProp1076choline TMA-lyase system