Genome Property Definition Page
| Accession | GenProp0273 | |
| Name | protocatechuate degradation to beta-ketoadipate | |
| Type | PATHWAY | |
| Description | This pathway represents the bacterial version of degradation of protocatechuate to beta-ketoadipate. It is often referred to as the protocatechuate branch of the beta-ketoadipate pathway, in contrast to the catechol branch. Protocatechuate can be reached in one step from 3-hydroxybenzoate, 4-hydroxybenzoate, vanillate, etc, and in two steps from benzoate, and from other aromatic compounds. Note that catechol is another common intermediate in the degradation of aromatic compounds. The two branches converge at beta-ketoadipate. From there, beta-ketoadipate is degraded in a two-step pathway to succinyl-CoA and acetyl-CoA. | |
| JCVI Role | Other | |
| Parent Property | GenProp0142: catabolism | |
| Literature References |
| |
| Gene Ontology Term | GO:0019619: protocatechuate catabolic process (biological_process) |
Components
| Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
|---|---|---|---|---|
| protocatechuate 3,4-dioxygenase, alpha subunit | 1_pcaG | YES | TIGR02423 (HMM): protocatechuate 3,4-dioxygenase, alpha subunit | GO:0019619: protocatechuate catabolic process |
| protocatechuate 3,4-dioxygenase, beta subunit | 1_pcaH | YES | TIGR02422 (HMM): protocatechuate 3,4-dioxygenase, beta subunit | GO:0019619: protocatechuate catabolic process |
| 3-carboxy-cis,cis-muconate cycloisomerase | 2_pcaB | YES | TIGR02426 (HMM): 3-carboxy-cis,cis-muconate cycloisomerase | GO:0019619: protocatechuate catabolic process |
| 4-carboxymuconolactone decarboxylase | 3_pcaC | YES | TIGR02425 (HMM): 4-carboxymuconolactone decarboxylase | GO:0019619: protocatechuate catabolic process |
| 3-oxoadipate enol-lactonase | 4_pcaD | YES | TIGR02427 (HMM): 3-oxoadipate enol-lactonase | GO:0019619: protocatechuate catabolic process |
| Pca operon transcriptional regulator PcaQ | pcaQ | NO | TIGR02424 (HMM): pca operon transcription factor PcaQ | |
| regulators, PcaR/PcaU/PobR family | pcaR | NO | TIGR02431 (HMM): beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family |
Parent Properties
| Accession | Name |
|---|---|
| GenProp0142 | catabolism |
Sibling Properties
| Accession | Name |
|---|---|
| GenProp0055 | polyhydroxyalkanoic acids |
| GenProp0141 | galactose-6-phosphate degradation via tagatose-6-phosphate |
| GenProp0156 | cyanophycin-like storage polymers |
| GenProp0168 | glycogen system |
| GenProp0210 | phenylacetic acid catabolism |
| GenProp0231 | 4-hydroxyphenylacetate degradation |
| GenProp0233 | GABA utilization |
| GenProp0238 | 2-aminoethylphosphonate catabolism to acetaldehyde |
| GenProp0239 | propionyl-CoA catabolism |
| GenProp0241 | phosphonate catabolism |
| GenProp0271 | trehalose utilization |
| GenProp0272 | pyruvate fermentation to acetoin |
| GenProp0283 | beta-ketoadipate degradation to succinyl-CoA and acetyl-CoA |
| GenProp0294 | ethanolamine degradation proteinaceous organelle |
| GenProp0457 | rhamnose catabolism |
| GenProp0458 | fucose catabolism |
| GenProp0461 | utilization of deoxynucleosides |
| GenProp0653 | ectoine catabolism |
| GenProp0674 | malonate decarboxylase |
| GenProp0686 | allantoin catabolism to glyoxalate and urea |
| GenProp0687 | allantoin catabolism to oxamate and carbamoyl-phosphate |
| GenProp0688 | urate catabolism to allantoin |
| GenProp0691 | glycolysis |
| GenProp0693 | fructose utilization as fructose-1,6-bisphosphate |
| GenProp0694 | glucose utilization as fructose-1,6-bisphosphate |
| GenProp0700 | purine catabolism via urate, xanthine and allantoin |
| GenProp0702 | benzoyl-CoA reductase |
| GenProp0703 | 4-hydroxybenzoyl-CoA reductase |
| GenProp0706 | cyclohexa-1,5-diene-1-carbonyl-CoA to 3-hydroxypimelyl-CoA, dch/had/oah pathway |
| GenProp0708 | catechol meta-cleavage pathway |
| GenProp0709 | benzoate catabolism BoxABC pathway |
| GenProp0711 | catechol ortho-cleavage upper pathway |
| GenProp0714 | galactarate utilization via tartronate semi-aldehyde |
| GenProp0715 | galactarate utilization via 2-oxoglutarate semialdehyde |
| GenProp0716 | glucarate utilization via tartronate semi-aldehyde |
| GenProp0717 | glucarate utilization via 2-oxoglutarate semialdehyde |
| GenProp0718 | oxalate degradation |
| GenProp0734 | amino acid catabolism |
| GenProp0749 | choline sulfate utilization |
| GenProp0760 | putrescine degradation to GABA via gamma-glutamylation |
| GenProp0763 | nicotinate fermentation to pyruvate and propionate |
| GenProp0810 | encapsulin proteinaceous organelle |
| GenProp0813 | pyrimidine utilization operon, RutABCDEFGR |
| GenProp0902 | quinohemoprotein amine dehydrogenase |
| GenProp1071 | myo-inositol catabolism |
| GenProp1072 | cyanase system |
| GenProp1076 | choline TMA-lyase system |