Genome Property Definition Page

Nameethanolamine degradation proteinaceous organelle
DescriptionEthanolamine can be broken down to acetaldehyde by the action of ethanolamine ammonia lyase, an adenosyl cobalamin (vitamin B12) dependent enzyme. In its simplest form this system consists only of the two subunits of the enzyme, but ususally also includes a transporter for ethanolamine and may include a coexpressed acetaldehyde dehydrogenase to ensure that the toxic aldehyde is efficiently converted to acetyl-CoA. A more complex version of this system exists (GenProp0292) which includes additional genes coding for the proteinaceous coat of a specialized organelle as well as other genes for the efficienct maintenance and regulation of the lyase, handling of the product and import of the substrate. Presumably, this organellar system in organisms which may rely on ethanolamine as a primary carbon source.
Parent PropertyGenProp0142: catabolism
GenProp0284: cobalamin-utilizing enzymes
Literature References
[ 1 ]Roof DM, Roth JR  Ethanolamine utilization in Salmonella typhimurium.  J Bacteriol 1988 Sep;170(9):3855-63.  PMID 3045078
Gene Ontology TermGO:0046336: ethanolamine catabolic process (biological_process)

Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
ethanolamine ammonia-lyase, large subuniteutBYESPF06751 (HMM): ethanolamine ammonia-lyase, large subunitGO:0046336: ethanolamine catabolic process
ethanolamine ammonia-lyase, small subuniteutCYESPF05985 (HMM): ethanolamine ammonia-lyase, light subunitGO:0046336: ethanolamine catabolic process
putative acetaldehyde dehydrogenase (acetylating)eutENOTIGR02518 (HMM): acetaldehyde dehydrogenase (acetylating)
PF00171 (HMM-CLUST): aldehyde dehydrogenase (NAD) family protein
GO:0046336: ethanolamine catabolic process
GO:0046336: ethanolamine catabolic process
ethanolamine diffusion facilitatoreutHNOTIGR00908 (HMM): ethanolamine permease
PF04346 (HMM): ethanolamine utilisation protein EutH
GO:0046336: ethanolamine catabolic process
GO:0046336: ethanolamine catabolic process

Parent Properties
GenProp0284cobalamin-utilizing enzymes

Child Properties
GenProp0292ethanolamine degradation organelle

Sibling Properties
GenProp0055polyhydroxyalkanoic acids
GenProp0141galactose-6-phosphate degradation via tagatose-6-phosphate
GenProp0156cyanophycin-like storage polymers
GenProp0168glycogen system
GenProp0210phenylacetic acid catabolism
GenProp02314-hydroxyphenylacetate degradation
GenProp0233GABA utilization
GenProp02382-aminoethylphosphonate catabolism to acetaldehyde
GenProp0239propionyl-CoA catabolism
GenProp0241phosphonate catabolism
GenProp0271trehalose utilization
GenProp0272pyruvate fermentation to acetoin
GenProp0273protocatechuate degradation to beta-ketoadipate
GenProp0283beta-ketoadipate degradation to succinyl-CoA and acetyl-CoA
GenProp0457rhamnose catabolism
GenProp0458fucose catabolism
GenProp0461utilization of deoxynucleosides
GenProp0653ectoine catabolism
GenProp0674malonate decarboxylase
GenProp0686allantoin catabolism to glyoxalate and urea
GenProp0687allantoin catabolism to oxamate and carbamoyl-phosphate
GenProp0688urate catabolism to allantoin
GenProp0693fructose utilization as fructose-1,6-bisphosphate
GenProp0694glucose utilization as fructose-1,6-bisphosphate
GenProp0700purine catabolism via urate, xanthine and allantoin
GenProp0702benzoyl-CoA reductase
GenProp07034-hydroxybenzoyl-CoA reductase
GenProp0706cyclohexa-1,5-diene-1-carbonyl-CoA to 3-hydroxypimelyl-CoA, dch/had/oah pathway
GenProp0708catechol meta-cleavage pathway
GenProp0709benzoate catabolism BoxABC pathway
GenProp0711catechol ortho-cleavage upper pathway
GenProp0714galactarate utilization via tartronate semi-aldehyde
GenProp0715galactarate utilization via 2-oxoglutarate semialdehyde
GenProp0716glucarate utilization via tartronate semi-aldehyde
GenProp0717glucarate utilization via 2-oxoglutarate semialdehyde
GenProp0718oxalate degradation
GenProp0734amino acid catabolism
GenProp0749choline sulfate utilization
GenProp0760putrescine degradation to GABA via gamma-glutamylation
GenProp0763nicotinate fermentation to pyruvate and propionate
GenProp0810encapsulin proteinaceous organelle
GenProp0813pyrimidine utilization operon, RutABCDEFGR
GenProp0902quinohemoprotein amine dehydrogenase
GenProp1071myo-inositol catabolism
GenProp1072cyanase system
GenProp1076choline TMA-lyase system
GenProp0288tetrahydromethanopterin S-methyltransferase complex
GenProp0290class II (B12-dependent) ribonucleotide reductase