Genome Property Definition Page
| Accession | GenProp0294 | |
| Name | ethanolamine degradation proteinaceous organelle | |
| Type | SYSTEM | |
| Description | Ethanolamine can be broken down to acetaldehyde by the action of ethanolamine ammonia lyase, an adenosyl cobalamin (vitamin B12) dependent enzyme. In its simplest form this system consists only of the two subunits of the enzyme, but ususally also includes a transporter for ethanolamine and may include a coexpressed acetaldehyde dehydrogenase to ensure that the toxic aldehyde is efficiently converted to acetyl-CoA. A more complex version of this system exists (GenProp0292) which includes additional genes coding for the proteinaceous coat of a specialized organelle as well as other genes for the efficienct maintenance and regulation of the lyase, handling of the product and import of the substrate. Presumably, this organellar system in organisms which may rely on ethanolamine as a primary carbon source. | |
| Parent Property | GenProp0142: catabolism GenProp0284: cobalamin-utilizing enzymes | |
| Literature References |
| |
| Gene Ontology Term | GO:0046336: ethanolamine catabolic process (biological_process) |
Components
| Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
|---|---|---|---|---|
| ethanolamine ammonia-lyase, large subunit | eutB | YES | PF06751 (HMM): ethanolamine ammonia-lyase, large subunit | GO:0046336: ethanolamine catabolic process |
| ethanolamine ammonia-lyase, small subunit | eutC | YES | PF05985 (HMM): ethanolamine ammonia-lyase, light subunit | GO:0046336: ethanolamine catabolic process |
| putative acetaldehyde dehydrogenase (acetylating) | eutE | NO | TIGR02518 (HMM): acetaldehyde dehydrogenase (acetylating) PF00171 (HMM-CLUST): aldehyde dehydrogenase (NAD) family protein | GO:0046336: ethanolamine catabolic process GO:0046336: ethanolamine catabolic process |
| ethanolamine diffusion facilitator | eutH | NO | TIGR00908 (HMM): ethanolamine permease PF04346 (HMM): ethanolamine utilisation protein EutH | GO:0046336: ethanolamine catabolic process GO:0046336: ethanolamine catabolic process |
Parent Properties
| Accession | Name |
|---|---|
| GenProp0142 | catabolism |
| GenProp0284 | cobalamin-utilizing enzymes |
Child Properties
| Accession | Name |
|---|---|
| GenProp0292 | ethanolamine degradation organelle |
Sibling Properties
| Accession | Name |
|---|---|
| GenProp0055 | polyhydroxyalkanoic acids |
| GenProp0141 | galactose-6-phosphate degradation via tagatose-6-phosphate |
| GenProp0156 | cyanophycin-like storage polymers |
| GenProp0168 | glycogen system |
| GenProp0210 | phenylacetic acid catabolism |
| GenProp0231 | 4-hydroxyphenylacetate degradation |
| GenProp0233 | GABA utilization |
| GenProp0238 | 2-aminoethylphosphonate catabolism to acetaldehyde |
| GenProp0239 | propionyl-CoA catabolism |
| GenProp0241 | phosphonate catabolism |
| GenProp0271 | trehalose utilization |
| GenProp0272 | pyruvate fermentation to acetoin |
| GenProp0273 | protocatechuate degradation to beta-ketoadipate |
| GenProp0283 | beta-ketoadipate degradation to succinyl-CoA and acetyl-CoA |
| GenProp0457 | rhamnose catabolism |
| GenProp0458 | fucose catabolism |
| GenProp0461 | utilization of deoxynucleosides |
| GenProp0653 | ectoine catabolism |
| GenProp0674 | malonate decarboxylase |
| GenProp0686 | allantoin catabolism to glyoxalate and urea |
| GenProp0687 | allantoin catabolism to oxamate and carbamoyl-phosphate |
| GenProp0688 | urate catabolism to allantoin |
| GenProp0691 | glycolysis |
| GenProp0693 | fructose utilization as fructose-1,6-bisphosphate |
| GenProp0694 | glucose utilization as fructose-1,6-bisphosphate |
| GenProp0700 | purine catabolism via urate, xanthine and allantoin |
| GenProp0702 | benzoyl-CoA reductase |
| GenProp0703 | 4-hydroxybenzoyl-CoA reductase |
| GenProp0706 | cyclohexa-1,5-diene-1-carbonyl-CoA to 3-hydroxypimelyl-CoA, dch/had/oah pathway |
| GenProp0708 | catechol meta-cleavage pathway |
| GenProp0709 | benzoate catabolism BoxABC pathway |
| GenProp0711 | catechol ortho-cleavage upper pathway |
| GenProp0714 | galactarate utilization via tartronate semi-aldehyde |
| GenProp0715 | galactarate utilization via 2-oxoglutarate semialdehyde |
| GenProp0716 | glucarate utilization via tartronate semi-aldehyde |
| GenProp0717 | glucarate utilization via 2-oxoglutarate semialdehyde |
| GenProp0718 | oxalate degradation |
| GenProp0734 | amino acid catabolism |
| GenProp0749 | choline sulfate utilization |
| GenProp0760 | putrescine degradation to GABA via gamma-glutamylation |
| GenProp0763 | nicotinate fermentation to pyruvate and propionate |
| GenProp0810 | encapsulin proteinaceous organelle |
| GenProp0813 | pyrimidine utilization operon, RutABCDEFGR |
| GenProp0902 | quinohemoprotein amine dehydrogenase |
| GenProp1071 | myo-inositol catabolism |
| GenProp1072 | cyanase system |
| GenProp1076 | choline TMA-lyase system |
| GenProp0288 | tetrahydromethanopterin S-methyltransferase complex |
| GenProp0290 | class II (B12-dependent) ribonucleotide reductase |