Genome Property Definition Page
| Accession | GenProp0763 | |
| Name | nicotinate fermentation to pyruvate and propionate | |
| Type | PATHWAY | |
| Description | This property represents one of a number of distinct catabolic pathways for nicotinate (niacin, vitamin B3), a nine-enzyme anaerobic fermentation to pyruvate and propionate as in the anaerobic soil bacterium Eubacterium barkeri. The nicotinate dehydrogenase in E. barkeri is a four-subunit enzyme with a non-selenocysteine selenium that belongs to a family of selenium-dependent molybdenum hydroxylases. | |
| JCVI Role | Other | |
| Parent Property | GenProp0142: catabolism GenProp0298: fermentation | |
| Literature References |
| |
| Gene Ontology Term | GO:0046497: nicotinate nucleotide metabolic process (biological_process) |
Components
| Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
|---|---|---|---|---|
| nicotinate dehydrogenase, FAD subunit | n1_ndhF | YES | 2080 (RULE_BASE) | GO:0046497: nicotinate nucleotide metabolic process |
| nicotinate dehydrogenase, NdhL subunit | n1_ndhL | YES | ||
| nicotinate dehydrogenase, NdhM subunit | n1_ndhM | YES | ||
| nicotinate dehydrogenase, 2x[2Fe-2S] subunit | n1_ndhS | YES | 2081 (RULE_BASE) | GO:0046497: nicotinate nucleotide metabolic process |
| 6-hydroxynicotinate reductase (1.3.7.1) | nic_2 | YES | ||
| enamidase (3.5.2.18) | nic_3 | YES | 2082 (RULE_BASE) | GO:0046497: nicotinate nucleotide metabolic process |
| 2-hydroxymethylglutarate dehydrogenase (1.1.1.291) | nic_4 | YES | ||
| 2-hydroxymethylglutarate dehydratase | nic_5 | YES | ||
| 2-methyleneglutarate mutase (5.4.99.4) | nic_6 | YES | 2079 (RULE_BASE) | GO:0046497: nicotinate nucleotide metabolic process |
| methylitaconate Delta-isomerase (5.3.3.6) | nic_7 | YES | ||
| dimethylmaleate hydratase (4.2.1.85) | nic_8 | YES | ||
| 2,3-dimethylmalate lyase (4.1.3.32) | nic_9 | YES |
Parent Properties
| Accession | Name |
|---|---|
| GenProp0142 | catabolism |
| GenProp0298 | fermentation |
Sibling Properties
| Accession | Name |
|---|---|
| GenProp0055 | polyhydroxyalkanoic acids |
| GenProp0141 | galactose-6-phosphate degradation via tagatose-6-phosphate |
| GenProp0156 | cyanophycin-like storage polymers |
| GenProp0168 | glycogen system |
| GenProp0210 | phenylacetic acid catabolism |
| GenProp0231 | 4-hydroxyphenylacetate degradation |
| GenProp0233 | GABA utilization |
| GenProp0238 | 2-aminoethylphosphonate catabolism to acetaldehyde |
| GenProp0239 | propionyl-CoA catabolism |
| GenProp0241 | phosphonate catabolism |
| GenProp0271 | trehalose utilization |
| GenProp0272 | pyruvate fermentation to acetoin |
| GenProp0273 | protocatechuate degradation to beta-ketoadipate |
| GenProp0283 | beta-ketoadipate degradation to succinyl-CoA and acetyl-CoA |
| GenProp0294 | ethanolamine degradation proteinaceous organelle |
| GenProp0457 | rhamnose catabolism |
| GenProp0458 | fucose catabolism |
| GenProp0461 | utilization of deoxynucleosides |
| GenProp0653 | ectoine catabolism |
| GenProp0674 | malonate decarboxylase |
| GenProp0686 | allantoin catabolism to glyoxalate and urea |
| GenProp0687 | allantoin catabolism to oxamate and carbamoyl-phosphate |
| GenProp0688 | urate catabolism to allantoin |
| GenProp0691 | glycolysis |
| GenProp0693 | fructose utilization as fructose-1,6-bisphosphate |
| GenProp0694 | glucose utilization as fructose-1,6-bisphosphate |
| GenProp0700 | purine catabolism via urate, xanthine and allantoin |
| GenProp0702 | benzoyl-CoA reductase |
| GenProp0703 | 4-hydroxybenzoyl-CoA reductase |
| GenProp0706 | cyclohexa-1,5-diene-1-carbonyl-CoA to 3-hydroxypimelyl-CoA, dch/had/oah pathway |
| GenProp0708 | catechol meta-cleavage pathway |
| GenProp0709 | benzoate catabolism BoxABC pathway |
| GenProp0711 | catechol ortho-cleavage upper pathway |
| GenProp0714 | galactarate utilization via tartronate semi-aldehyde |
| GenProp0715 | galactarate utilization via 2-oxoglutarate semialdehyde |
| GenProp0716 | glucarate utilization via tartronate semi-aldehyde |
| GenProp0717 | glucarate utilization via 2-oxoglutarate semialdehyde |
| GenProp0718 | oxalate degradation |
| GenProp0734 | amino acid catabolism |
| GenProp0749 | choline sulfate utilization |
| GenProp0760 | putrescine degradation to GABA via gamma-glutamylation |
| GenProp0810 | encapsulin proteinaceous organelle |
| GenProp0813 | pyrimidine utilization operon, RutABCDEFGR |
| GenProp0902 | quinohemoprotein amine dehydrogenase |
| GenProp1071 | myo-inositol catabolism |
| GenProp1072 | cyanase system |
| GenProp1076 | choline TMA-lyase system |
| GenProp0765 | glycerol fermentation to 1,3-propanediol, using glycerol dehydratase |