Genome Property Definition Page
Accession | GenProp0686 | |
Name | allantoin catabolism to glyoxalate and urea | |
Type | METAPATH | |
Description | (S)-allantoin ([(4S)-2,5-dioxoimidazolidin-4-yl]urea) is a breakdown product of urate and may be obtained by an endogenous urate catabolism pathway or by transport from the environment. Catabolism of allantoate consists of a three-step pathway resulting in glyoxalate. This is further processed to tartronate semi-aldehyde (2-hydroxy-3-oxopropanoate) and subsequently to either phyosphoglycerate or glycoaldehyde (in the pathway to the pyridoxine component of vitamin B6). Since many pathways result in glyoxalate, this genome property terminates at that compound although the downsream enzymes may be grouped into apparent operons in many organisms (i.e. E. coli). Degradation of allantoin results in the production of two molecules of urea which may be excreted or used as a source of ammonia in urease-containing organisms. | |
JCVI Role | Other | |
Parent Property | GenProp0142: catabolism | |
Literature References |
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Gene Ontology Term | GO:0009442: allantoin assimilation pathway (biological_process) |
Components
Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
---|---|---|---|---|
source of (S)-allantoin | all-in | NO | TIGR00800 (HMM-CLUST): NCS1 nucleoside transporter familyGenProp0688 (GENPROP): urate catabolism to allantoin | GO:0009442: allantoin assimilation pathway GO:0009442: allantoin assimilation pathway |
ureidoglycolate lyase (4.3.2.3) | allA | YES | PF04115 (HMM): ureidoglycolate lyase | GO:0009442: allantoin assimilation pathway |
allantoinase (3.5.2.5) | allB | YES | TIGR03178 (HMM): allantoinase | GO:0009442: allantoin assimilation pathway |
allantoin hydrolysis, final | allC-f | NO | TIGR02961 (HMM): allantoicase | GO:0009442: allantoin assimilation pathway |
allantoin hydrolysis, initial | allC-i | YES | TIGR02961 (HMM): allantoicase TIGR03176 (HMM): allantoate amidohydrolase | GO:0009442: allantoin assimilation pathway GO:0009442: allantoin assimilation pathway |
cupin domain protein, unknown function | allX | NO | TIGR03214 (HMM): putative allantoin catabolism protein | GO:0009442: allantoin assimilation pathway |
Parent Properties
Accession | Name |
---|---|
GenProp0142 | catabolism |
Sibling Properties
Accession | Name |
---|---|
GenProp0055 | polyhydroxyalkanoic acids |
GenProp0141 | galactose-6-phosphate degradation via tagatose-6-phosphate |
GenProp0156 | cyanophycin-like storage polymers |
GenProp0168 | glycogen system |
GenProp0210 | phenylacetic acid catabolism |
GenProp0231 | 4-hydroxyphenylacetate degradation |
GenProp0233 | GABA utilization |
GenProp0238 | 2-aminoethylphosphonate catabolism to acetaldehyde |
GenProp0239 | propionyl-CoA catabolism |
GenProp0241 | phosphonate catabolism |
GenProp0271 | trehalose utilization |
GenProp0272 | pyruvate fermentation to acetoin |
GenProp0273 | protocatechuate degradation to beta-ketoadipate |
GenProp0283 | beta-ketoadipate degradation to succinyl-CoA and acetyl-CoA |
GenProp0294 | ethanolamine degradation proteinaceous organelle |
GenProp0457 | rhamnose catabolism |
GenProp0458 | fucose catabolism |
GenProp0461 | utilization of deoxynucleosides |
GenProp0653 | ectoine catabolism |
GenProp0674 | malonate decarboxylase |
GenProp0687 | allantoin catabolism to oxamate and carbamoyl-phosphate |
GenProp0688 | urate catabolism to allantoin |
GenProp0691 | glycolysis |
GenProp0693 | fructose utilization as fructose-1,6-bisphosphate |
GenProp0694 | glucose utilization as fructose-1,6-bisphosphate |
GenProp0700 | purine catabolism via urate, xanthine and allantoin |
GenProp0702 | benzoyl-CoA reductase |
GenProp0703 | 4-hydroxybenzoyl-CoA reductase |
GenProp0706 | cyclohexa-1,5-diene-1-carbonyl-CoA to 3-hydroxypimelyl-CoA, dch/had/oah pathway |
GenProp0708 | catechol meta-cleavage pathway |
GenProp0709 | benzoate catabolism BoxABC pathway |
GenProp0711 | catechol ortho-cleavage upper pathway |
GenProp0714 | galactarate utilization via tartronate semi-aldehyde |
GenProp0715 | galactarate utilization via 2-oxoglutarate semialdehyde |
GenProp0716 | glucarate utilization via tartronate semi-aldehyde |
GenProp0717 | glucarate utilization via 2-oxoglutarate semialdehyde |
GenProp0718 | oxalate degradation |
GenProp0734 | amino acid catabolism |
GenProp0749 | choline sulfate utilization |
GenProp0760 | putrescine degradation to GABA via gamma-glutamylation |
GenProp0763 | nicotinate fermentation to pyruvate and propionate |
GenProp0810 | encapsulin proteinaceous organelle |
GenProp0813 | pyrimidine utilization operon, RutABCDEFGR |
GenProp0902 | quinohemoprotein amine dehydrogenase |
GenProp1071 | myo-inositol catabolism |
GenProp1072 | cyanase system |
GenProp1076 | choline TMA-lyase system |