Genome Property Definition Page

Namephosphonate catabolism
DescriptionThe capability to degrade phosphonates is believed to consist minimally of a system for transporting phosphonate compounds (those with carbon-PO3 linkages) coupled with a pathway for the hydrolysis of such bonds. Two classes of system are known, those that handle broad classes of phosphonate compounds and those that handle specific molecules. Genomes with evidence for either system will be assigned the YES state for this property.
Parent PropertyGenProp0142: catabolism
GenProp0242: phosphorus metabolism
Literature References
[ 1 ]Lee KS, Metcalf WW, Wanner BL  Evidence for two phosphonate degradative pathways in Enterobacter aerogenes.  J Bacteriol 1992 Apr;174(8):2501-10.  PMID 1556070
[ 2 ]Metcalf WW, Wanner BL  Evidence for a fourteen-gene, phnC to phnP locus for phosphonate metabolism in Escherichia coli.  Gene 1993 Jul 15;129(1):27-32.  PMID 8335257
[ 3 ]White AK, Metcalf WW  Two C-P lyase operons in Pseudomonas stutzeri and their roles in the oxidation of phosphonates, phosphite, and hypophosphite.  J Bacteriol 2004 Jul;186(14):4730-9.  PMID 15231805
[ 4 ]Kononova SV, Nesmeyanova MA  Phosphonates and their degradation by microorganisms.  Biochemistry (Mosc) 2002 Feb;67(2):184-95.  PMID 11952414
Gene Ontology TermGO:0019700: organic phosphonate catabolic process (biological_process)

Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
Phosphonate catabolism operons associated proteinsassocNOTIGR03364 (HMM): FAD dependent oxidoreductase TIGR03364
TIGR03276 (HMM): phosphonate degradation operons associated HDIG domain protein
GO:0019700: organic phosphonate catabolic process
GO:0019700: organic phosphonate catabolic process
phosphonate utilization systemsphn_catYESGenProp0232 (GENPROP): phosphonates C-P lyase system
GenProp0720 (GENPROP): 2-aminoethylphosphonate utilization
GO:0019700: organic phosphonate catabolic process
GO:0019700: organic phosphonate catabolic process

Parent Properties
GenProp0242phosphorus metabolism

Child Properties
GenProp0232phosphonates C-P lyase system
GenProp0710generic phosphonates utilization
GenProp07122-aminoethylphosphonate (AEP) ABC transporter, type I, PhnSTUV
GenProp07202-aminoethylphosphonate utilization
GenProp0736proposed phosphonate catabolism pathway HpnWXZ

Sibling Properties
GenProp0055polyhydroxyalkanoic acids
GenProp0141galactose-6-phosphate degradation via tagatose-6-phosphate
GenProp0156cyanophycin-like storage polymers
GenProp0168glycogen system
GenProp0210phenylacetic acid catabolism
GenProp02314-hydroxyphenylacetate degradation
GenProp0233GABA utilization
GenProp02382-aminoethylphosphonate catabolism to acetaldehyde
GenProp0239propionyl-CoA catabolism
GenProp0271trehalose utilization
GenProp0272pyruvate fermentation to acetoin
GenProp0273protocatechuate degradation to beta-ketoadipate
GenProp0283beta-ketoadipate degradation to succinyl-CoA and acetyl-CoA
GenProp0294ethanolamine degradation proteinaceous organelle
GenProp0457rhamnose catabolism
GenProp0458fucose catabolism
GenProp0461utilization of deoxynucleosides
GenProp0653ectoine catabolism
GenProp0674malonate decarboxylase
GenProp0686allantoin catabolism to glyoxalate and urea
GenProp0687allantoin catabolism to oxamate and carbamoyl-phosphate
GenProp0688urate catabolism to allantoin
GenProp0693fructose utilization as fructose-1,6-bisphosphate
GenProp0694glucose utilization as fructose-1,6-bisphosphate
GenProp0700purine catabolism via urate, xanthine and allantoin
GenProp0702benzoyl-CoA reductase
GenProp07034-hydroxybenzoyl-CoA reductase
GenProp0706cyclohexa-1,5-diene-1-carbonyl-CoA to 3-hydroxypimelyl-CoA, dch/had/oah pathway
GenProp0708catechol meta-cleavage pathway
GenProp0709benzoate catabolism BoxABC pathway
GenProp0711catechol ortho-cleavage upper pathway
GenProp0714galactarate utilization via tartronate semi-aldehyde
GenProp0715galactarate utilization via 2-oxoglutarate semialdehyde
GenProp0716glucarate utilization via tartronate semi-aldehyde
GenProp0717glucarate utilization via 2-oxoglutarate semialdehyde
GenProp0718oxalate degradation
GenProp0734amino acid catabolism
GenProp0749choline sulfate utilization
GenProp0760putrescine degradation to GABA via gamma-glutamylation
GenProp0763nicotinate fermentation to pyruvate and propionate
GenProp0810encapsulin proteinaceous organelle
GenProp0813pyrimidine utilization operon, RutABCDEFGR
GenProp0902quinohemoprotein amine dehydrogenase
GenProp1071myo-inositol catabolism
GenProp1072cyanase system
GenProp1076choline TMA-lyase system
GenProp0190phosphate ABC transporter (pstSCAB-phoU)
GenProp0243ATP synthases
GenProp0724phosphonoacetaldehyde biosynthesis from phosphoenolpyruvate