Genome Property Definition Page
| Accession | GenProp0844 | |
| Name | accessory Sec system for serine-rich glycoprotein transport | |
| Type | SYSTEM | |
| Description | A number of Gram-positive pathogens express serine-rich glycoproteins such as the platelet-binding glycoprotein GspB of Streptococcus gordonii. At least 5 core proteins contribute to the export of these proteins, including SecY2 and SecA2, homologs respectively of the SecY and SecA proteins of the Sec system. Additional proteins are required for glycosylation rather than export. | |
| JCVI Role | Protein and peptide secretion and trafficking | |
| Parent Property | GenProp0179: protein transport | |
| Literature References |
| |
| Gene Ontology Term | GO:0034436: glycoprotein transport (biological_process) |
Components
| Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
|---|---|---|---|---|
| serine-rich glycoprotein | S_rich | NO | TIGR03715 (HMM-CLUST): KxYKxGKxW signal peptide TIGR04224 (HMM): serine-rich repeat adhesion glycoprotein | |
| accessory Sec system translocase SecA2 | SecA2 | YES | TIGR03714 (HMM): accessory Sec system translocase SecA2 | GO:0034436: glycoprotein transport |
| accessory Sec system translocase SecY2 | SecY2 | YES | TIGR02920 (HMM): accessory Sec system translocase SecY2 | GO:0034436: glycoprotein transport |
| accessory Sec system protein Asp1 | accSec1 | YES | TIGR03713 (HMM): accessory Sec system protein Asp1 | GO:0034436: glycoprotein transport |
| accessory Sec system protein Asp2 | accSec2 | YES | TIGR03712 (HMM): accessory Sec system protein Asp2 | GO:0034436: glycoprotein transport |
| accessory Sec system protein Asp3 | accSec3 | YES | TIGR03711 (HMM): accessory Sec system protein Asp3 | GO:0034436: glycoprotein transport |
| accessory Sec system protein Asp4 | accSec4 | NO | 2379 (RULE_BASE) | GO:0034436: glycoprotein transport |
| accessory Sec system protein Asp5 | accSec5 | NO | 2378 (RULE_BASE) | GO:0034436: glycoprotein transport |
| accessory Sec system glycosyltransferase GtfA | gtfA | NO | TIGR02918 (HMM): accessory Sec system glycosylation protein GtfA | |
| accessory Sec system glycosyltransferase GtfB | gtfB | NO | TIGR02919 (HMM): accessory Sec system glycosyltransferase GtfB |
Parent Properties
| Accession | Name |
|---|---|
| GenProp0179 | protein transport |
Sibling Properties
| Accession | Name |
|---|---|
| GenProp0052 | type III secretion |
| GenProp0053 | type II secretion |
| GenProp0054 | type IV secretion |
| GenProp0059 | type I secretion |
| GenProp0127 | Tat (Sec-independent) protein export |
| GenProp0205 | signal recognition system, bacterial |
| GenProp0207 | lipoprotein localization system lolABCDE |
| GenProp0209 | Sec system preprotein translocase |
| GenProp0295 | prokaryotic N-terminal cleavage/methylation, type IV pilin-like |
| GenProp0326 | protein sorting system, PEP-CTERM/exosortase (generic) |
| GenProp0626 | protein sorting system, sortase type, LPXTG/SrtA class |
| GenProp0664 | protein sorting system, sortase type, SrtB class |
| GenProp0669 | protein sorting system, putative, exosortase G class |
| GenProp0735 | type VI secretion |
| GenProp0778 | protein sorting system, GlyGly-CTERM/rhombosortase |
| GenProp0845 | protein sorting system, KxYKxGKxW class |
| GenProp0847 | exosporium |
| GenProp0859 | protein sorting system, proteobacterial dedicated sortase type |
| GenProp0904 | type VII secretion, Actinobacteria form |
| GenProp0905 | type VII secretion, Firmicutes form |
| GenProp0928 | OMP chaperone system: SurA-Skp-DegP |
| GenProp0957 | protein sorting system, SipW class |
| GenProp0978 | protein sorting system, PGF-CTERM/archaeosortase A |
| GenProp0979 | protein sorting system, PEF-CTERM/archaeosortase C |
| GenProp0980 | protein sorting system, putative, exosortase F class |
| GenProp0983 | protein sorting system, VPXXXP-CTERM/archaeosortase B |
| GenProp0985 | protein sorting system, VPDSG-CTERM/exosortase C |
| GenProp0986 | protein sorting system, VPLPA-CTERM/exosortase D |
| GenProp0987 | protein sorting system, cyano-PEP-CTERM class |
| GenProp0989 | protein sorting system, VPEID-CTERM/exosortase E |
| GenProp0993 | protein sorting system, PIP-CTERM/archaeosortase D |
| GenProp0996 | protein sorting system, IPTLxxWG-CTERM/exosortase H |
| GenProp0999 | Por secretion system |
| GenProp1005 | protein sorting system, putative, exosortase J class |
| GenProp1054 | protein sorting system, MSEP-CTERM/exosortase K |
| GenProp1055 | protein sorting system, PEFG-CTERM/thaumarchaeosortase |
| GenProp1074 | type V secretion |
| GenProp1087 | protein sorting system, vault protein/exosortase N |
| GenProp1102 | protein sorting system, CGP-CTERM/unknown of Thermococcaceae |
| GenProp1103 | protein sorting system, Synergist-CTERM/unknown of Synergistetes |