Genome Property Definition Page
| Accession | GenProp0904 | |
| Name | type VII secretion, Actinobacteria form | |
| Type | SYSTEM | |
| Description | Type VII secretion (T7S) is also called ESAT-6-, SNM-, and ESX-secretion. It occurs in Mycobacterium, which has an impermeable cell envelope that contains long-chain mycolic acids in an outer membrane, and T7S provides a means to transport proteins through this barrier. Multiple T7S loci can occur in one species, with different secretion targets for different systems. The system includes a subtilisin-like protease called mycosin and membrane proteins with a new nomenclature in starting with ecc (esx conserved component). | |
| JCVI Role | Protein and peptide secretion and trafficking | |
| Parent Property | GenProp0179: protein transport | |
| Literature References |
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Components
| Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
|---|---|---|---|---|
| type VII secretion AAA-ATPase EccA | T7_EccA | YES | TIGR03922 (HMM): type VII secretion AAA-ATPase EccA | |
| type VII secretion transmembrane protein EccB | T7_EccB | YES | TIGR03919 (HMM): type VII secretion protein EccB | |
| type VII secretion protein EccC | T7_EccC | YES | TIGR03924 (HMM): type VII secretion protein EccCa TIGR03925 (HMM): type VII secretion protein EccCb | |
| type VII secretion integral membrane protein EccD | T7_EccD | YES | TIGR03920 (HMM): type VII secretion integral membrane protein EccD | |
| type VII secretion transmembrane protein EccE | T7_EccE | YES | TIGR03923 (HMM): type VII secretion protein EccE | |
| WXG100 family type VII secretion target | T7_WxG | YES | PF06013 (HMM-CLUST): WXG motif protein TIGR03930 (HMM-CLUST): WXG100 family type VII secretion target | |
| type VII secretion-associated protein, Rv3446c family | T7_a | NO | TIGR03931 (HMM): type VII secretion-associated protein, Rv3446c family | |
| mycosin | T7_myco | YES | TIGR03921 (HMM): type VII secretion-associated serine protease mycosin |
Parent Properties
| Accession | Name |
|---|---|
| GenProp0179 | protein transport |
Sibling Properties
| Accession | Name |
|---|---|
| GenProp0052 | type III secretion |
| GenProp0053 | type II secretion |
| GenProp0054 | type IV secretion |
| GenProp0059 | type I secretion |
| GenProp0127 | Tat (Sec-independent) protein export |
| GenProp0205 | signal recognition system, bacterial |
| GenProp0207 | lipoprotein localization system lolABCDE |
| GenProp0209 | Sec system preprotein translocase |
| GenProp0295 | prokaryotic N-terminal cleavage/methylation, type IV pilin-like |
| GenProp0326 | protein sorting system, PEP-CTERM/exosortase (generic) |
| GenProp0626 | protein sorting system, sortase type, LPXTG/SrtA class |
| GenProp0664 | protein sorting system, sortase type, SrtB class |
| GenProp0669 | protein sorting system, putative, exosortase G class |
| GenProp0735 | type VI secretion |
| GenProp0778 | protein sorting system, GlyGly-CTERM/rhombosortase |
| GenProp0844 | accessory Sec system for serine-rich glycoprotein transport |
| GenProp0845 | protein sorting system, KxYKxGKxW class |
| GenProp0847 | exosporium |
| GenProp0859 | protein sorting system, proteobacterial dedicated sortase type |
| GenProp0905 | type VII secretion, Firmicutes form |
| GenProp0928 | OMP chaperone system: SurA-Skp-DegP |
| GenProp0957 | protein sorting system, SipW class |
| GenProp0978 | protein sorting system, PGF-CTERM/archaeosortase A |
| GenProp0979 | protein sorting system, PEF-CTERM/archaeosortase C |
| GenProp0980 | protein sorting system, putative, exosortase F class |
| GenProp0983 | protein sorting system, VPXXXP-CTERM/archaeosortase B |
| GenProp0985 | protein sorting system, VPDSG-CTERM/exosortase C |
| GenProp0986 | protein sorting system, VPLPA-CTERM/exosortase D |
| GenProp0987 | protein sorting system, cyano-PEP-CTERM class |
| GenProp0989 | protein sorting system, VPEID-CTERM/exosortase E |
| GenProp0993 | protein sorting system, PIP-CTERM/archaeosortase D |
| GenProp0996 | protein sorting system, IPTLxxWG-CTERM/exosortase H |
| GenProp0999 | Por secretion system |
| GenProp1005 | protein sorting system, putative, exosortase J class |
| GenProp1054 | protein sorting system, MSEP-CTERM/exosortase K |
| GenProp1055 | protein sorting system, PEFG-CTERM/thaumarchaeosortase |
| GenProp1074 | type V secretion |
| GenProp1087 | protein sorting system, vault protein/exosortase N |
| GenProp1102 | protein sorting system, CGP-CTERM/unknown of Thermococcaceae |
| GenProp1103 | protein sorting system, Synergist-CTERM/unknown of Synergistetes |