Genome Property Definition Page
| Accession | GenProp0928 | |
| Name | OMP chaperone system: SurA-Skp-DegP | |
| Type | SYSTEM | |
| Description | Outer membrane beta-barrel proteins are translocated into the periplasm by the Sec system and subsequently properly folded and inserted into the outer membrane by the beta-barrel assembly machine (Bam). In the periplasm chaperones prevent misfolding and aggregation and facilitate the transit across the periplasmic space. The SurA protein appears to be the primary chaperone, at least in E. coli [1], while Skp and DegP may act to rescue any OMPs which fall off of the SurA complex. | |
| Parent Property | GenProp0179: protein transport GenProp0248: protein folding GenProp0725: outer membrane protein assembly complex | |
| Literature References |
| |
| Gene Ontology Term | GO:0006886: intracellular protein transport (biological_process) |
Components
| Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
|---|---|---|---|---|
| chaperone DegP | DegP | YES | TIGR02037 (HMM): peptidase Do | GO:0006886: intracellular protein transport |
| chaperone Skp | Skp | YES | PF03938 (HMM): outer membrane protein, OmpH-like | GO:0006886: intracellular protein transport |
| chaperone SurA | SurA | YES | PF09312 (HMM): SurA N-terminal domain | GO:0006886: intracellular protein transport |
Parent Properties
| Accession | Name |
|---|---|
| GenProp0179 | protein transport |
| GenProp0248 | protein folding |
| GenProp0725 | outer membrane protein assembly complex |
Sibling Properties
| Accession | Name |
|---|---|
| GenProp0052 | type III secretion |
| GenProp0053 | type II secretion |
| GenProp0054 | type IV secretion |
| GenProp0059 | type I secretion |
| GenProp0127 | Tat (Sec-independent) protein export |
| GenProp0205 | signal recognition system, bacterial |
| GenProp0207 | lipoprotein localization system lolABCDE |
| GenProp0209 | Sec system preprotein translocase |
| GenProp0295 | prokaryotic N-terminal cleavage/methylation, type IV pilin-like |
| GenProp0326 | protein sorting system, PEP-CTERM/exosortase (generic) |
| GenProp0626 | protein sorting system, sortase type, LPXTG/SrtA class |
| GenProp0664 | protein sorting system, sortase type, SrtB class |
| GenProp0669 | protein sorting system, putative, exosortase G class |
| GenProp0735 | type VI secretion |
| GenProp0778 | protein sorting system, GlyGly-CTERM/rhombosortase |
| GenProp0844 | accessory Sec system for serine-rich glycoprotein transport |
| GenProp0845 | protein sorting system, KxYKxGKxW class |
| GenProp0847 | exosporium |
| GenProp0859 | protein sorting system, proteobacterial dedicated sortase type |
| GenProp0904 | type VII secretion, Actinobacteria form |
| GenProp0905 | type VII secretion, Firmicutes form |
| GenProp0957 | protein sorting system, SipW class |
| GenProp0978 | protein sorting system, PGF-CTERM/archaeosortase A |
| GenProp0979 | protein sorting system, PEF-CTERM/archaeosortase C |
| GenProp0980 | protein sorting system, putative, exosortase F class |
| GenProp0983 | protein sorting system, VPXXXP-CTERM/archaeosortase B |
| GenProp0985 | protein sorting system, VPDSG-CTERM/exosortase C |
| GenProp0986 | protein sorting system, VPLPA-CTERM/exosortase D |
| GenProp0987 | protein sorting system, cyano-PEP-CTERM class |
| GenProp0989 | protein sorting system, VPEID-CTERM/exosortase E |
| GenProp0993 | protein sorting system, PIP-CTERM/archaeosortase D |
| GenProp0996 | protein sorting system, IPTLxxWG-CTERM/exosortase H |
| GenProp0999 | Por secretion system |
| GenProp1005 | protein sorting system, putative, exosortase J class |
| GenProp1054 | protein sorting system, MSEP-CTERM/exosortase K |
| GenProp1055 | protein sorting system, PEFG-CTERM/thaumarchaeosortase |
| GenProp1074 | type V secretion |
| GenProp1087 | protein sorting system, vault protein/exosortase N |
| GenProp1102 | protein sorting system, CGP-CTERM/unknown of Thermococcaceae |
| GenProp1103 | protein sorting system, Synergist-CTERM/unknown of Synergistetes |
| GenProp0244 | chaperone system: DnaK-DnaJ-GrpE |
| GenProp0245 | chaperone system: GroEL/GroES |
| GenProp0246 | chaperone system: thermosome/prefoldin |
| GenProp0725 | outer membrane protein assembly complex |