Genome Property Definition Page

Accession	GenProp1103
Name	protein sorting system, Synergist-CTERM/unknown of Synergistetes
Type	SYSTEM
Description	This HMM describes a putative bacterial C-terminal protein-sorting system restricted to the Synergistetes, but not universal in that lineage. Model genomes from at least seven genera average ten proteins apiece with the Synergist-CTERM signal. Some protein-sorting signals have the signature motif separated from the transmembrane helix (TM) by a spacer region (e.g. LPXTG and MYXO-CTERM) while others are have it flush against the TM (PGF-CTERM, GlyGly-CTERM, and this one). The lack of spacer suggests that the unknown sorting enzyme is a multiple membrane-spanning protein, like archaeosortase and rhombosortase, rather than a predominantly hydrophilic enzyme like sortase, whose targets have a spacer.
Parent Property	GenProp0179: protein transport

Components

Step Name	Step Num	Required	Evidence (Method)	Evidence Go Terms
unknown sorting enzyme for Synergist-CTERM	sorter	YES
Synergist_CTERM protein sorting domain	target	YES	TIGR04564 (HMM): Synergist-CTERM protein sorting domain

Parent Properties

Accession	Name
GenProp0179	protein transport

Sibling Properties

Accession	Name
GenProp0052	type III secretion
GenProp0053	type II secretion
GenProp0054	type IV secretion
GenProp0059	type I secretion
GenProp0127	Tat (Sec-independent) protein export
GenProp0205	signal recognition system, bacterial
GenProp0207	lipoprotein localization system lolABCDE
GenProp0209	Sec system preprotein translocase
GenProp0295	prokaryotic N-terminal cleavage/methylation, type IV pilin-like
GenProp0326	protein sorting system, PEP-CTERM/exosortase (generic)
GenProp0626	protein sorting system, sortase type, LPXTG/SrtA class
GenProp0664	protein sorting system, sortase type, SrtB class
GenProp0669	protein sorting system, putative, exosortase G class
GenProp0735	type VI secretion
GenProp0778	protein sorting system, GlyGly-CTERM/rhombosortase
GenProp0844	accessory Sec system for serine-rich glycoprotein transport
GenProp0845	protein sorting system, KxYKxGKxW class
GenProp0847	exosporium
GenProp0859	protein sorting system, proteobacterial dedicated sortase type
GenProp0904	type VII secretion, Actinobacteria form
GenProp0905	type VII secretion, Firmicutes form
GenProp0928	OMP chaperone system: SurA-Skp-DegP
GenProp0957	protein sorting system, SipW class
GenProp0978	protein sorting system, PGF-CTERM/archaeosortase A
GenProp0979	protein sorting system, PEF-CTERM/archaeosortase C
GenProp0980	protein sorting system, putative, exosortase F class
GenProp0983	protein sorting system, VPXXXP-CTERM/archaeosortase B
GenProp0985	protein sorting system, VPDSG-CTERM/exosortase C
GenProp0986	protein sorting system, VPLPA-CTERM/exosortase D
GenProp0987	protein sorting system, cyano-PEP-CTERM class
GenProp0989	protein sorting system, VPEID-CTERM/exosortase E
GenProp0993	protein sorting system, PIP-CTERM/archaeosortase D
GenProp0996	protein sorting system, IPTLxxWG-CTERM/exosortase H
GenProp0999	Por secretion system
GenProp1005	protein sorting system, putative, exosortase J class
GenProp1054	protein sorting system, MSEP-CTERM/exosortase K
GenProp1055	protein sorting system, PEFG-CTERM/thaumarchaeosortase
GenProp1074	type V secretion
GenProp1087	protein sorting system, vault protein/exosortase N
GenProp1102	protein sorting system, CGP-CTERM/unknown of Thermococcaceae