Genome Property Definition Page

Namebeta-glutamate biosynthesis
DescriptionBeta-glutamate is an osmolyte produced in one step from glutamate by the action of glutamate 2,3-aminomutase. The eam gene, encoding glutamate 2,3-aminomutase, is often preceded by a ydaO (yuaA) family riboswitch, which appears to bind a metabolite that indicates cellular stress.
Parent PropertyGenProp0267: osmolyte biosynthesis
Literature References
[ 1 ]Ruzicka FJ, Frey PA  Glutamate 2,3-aminomutase: a new member of the radical SAM superfamily of enzymes.  Biochim Biophys Acta. 2007 Feb;1774(2):286-96.  PMID 17222594
[ 2 ]Block KF, Hammond MC, Breaker RR  Evidence for widespread gene control function by the ydaO riboswitch candidate.  J Bacteriol. 2010 Aug;192(15):3983-9. Epub 2010 May 28.  PMID 20511502

Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
glutamate 2,3-aminomutaseBetaGluYESTIGR04368 (HMM): glutamate 2,3-aminomutase

Parent Properties
GenProp0267osmolyte biosynthesis

Sibling Properties
GenProp0147glycine betaine biosynthesis from choline
GenProp0264glucosylglycerol biosynthesis
GenProp0265trehalose biosynthesis, OtsAB pathway
GenProp0266trehalose biosynthesis, TreYZ pathway
GenProp0268ectoine biosynthesis
GenProp0281mannosylglycerate biosynthesis
GenProp0878N(epsilon)-acetyl-beta-lysine biosynthesis