Description | Ectoine is a compatible solute used as an osmoprotectant by a number of bacterial species, including Vibrio cholerae, Halomonas variabilis, Bacillus pasteurii, Mycobacterium smegmatis, etc. Key enzymes are diaminobutyric acid acetyltransferase (EctA), diaminobutyric acid aminotransferase (EctB), and ectoine synthase (EctC). Ectoine is 1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid. Many ectoine-producing species contain the enzyme ectoine hydroxylase (EctD), and also produce hydroxyectoine. |
Literature References | [ 1 ]Kuhlmann AU, Bremer E Osmotically regulated synthesis of the compatible solute ectoine in Bacillus pasteurii and related Bacillus spp. Appl Environ Microbiol 2002 Feb;68(2):772-83. PMID 11823218 [ 2 ]Ofer N, Wishkautzan M, Meijler M, Wang Y, Speer A, Niederweis M, Gur E Ectoine biosynthesis in Mycobacterium smegmatis. Appl Environ Microbiol. 2012 Oct;78(20):7483-6. PMID 22885758 |
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