| Accession | GenProp0878 |
| Name | N(epsilon)-acetyl-beta-lysine biosynthesis |
| Type | PATHWAY |
| Description | N(epsilon)-acetyl-beta-lysine is a compatible solute produced in methanogenic archaea under salt stress. Note that the first enzyme in this two-step pathway can instead serve as the first step in lysine catabolism, as in Clostridium subterminale SB4 (see PMID:10629195). |
| JCVI Role | Adaptations to atypical conditions |
| Parent Property | GenProp0267: osmolyte biosynthesis
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| Literature References | [ 1 ] Pfluger K, Baumann S, Gottschalk G, Lin W, Santos H, Muller V Lysine-2,3-aminomutase and beta-lysine acetyltransferase genes of methanogenic archaea are salt induced and are essential for the biosynthesis of Nepsilon-acetyl-beta-lysine and growth at high salinity. Appl Environ Microbiol. 2003 Oct;69(10):6047-55. PMID 14532061
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| Gene Ontology Term | GO:0042398: cellular modified amino acid biosynthetic process (biological_process)
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