Genome Property Definition Page

Nameenergy-coupling factor transporters
DescriptionThis Genome Property consists of a form of ATP-energized transport in which two subunits resemble ABC transporter ATP-binding subunits, but the other two are distinct. The T component marks the transporter class, and generally is encoded adjacent the ATP-binding subunits. The substrate capture component S spans the membrane multiple times, and somewhat more than half the time is encoded away from the other subunits. In these systems, a single T subunit may transfer energy to a number of different S subunits.
JCVI RoleUnknown substrate
Parent PropertyGenProp0071: transport
Literature References
[ 1 ]Rodionov DA, Hebbeln P, Eudes A, ter Beek J, Rodionova IA, Erkens GB, Slotboom DJ, Gelfand MS, Osterman AL, Hanson AD, Eitinger T  A novel class of modular transporters for vitamins in prokaryotes.  J Bacteriol. 2009 Jan;191(1):42-51. doi: 10.1128/JB.01208-08.  PMID 18931129

Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
ECF transporter ATP-binding component 1ECFA1NOTIGR04520 (HMM): energy-coupling factor transporter ATPase
ECF transporter ATP-binding component 2ECFA2NOTIGR04521 (HMM): energy-coupling factor transporter ATPase
ECF transporter S componentECF_SYESPF02632 (HMM): BioY family
PF01891 (HMM): cobalt uptake substrate-specific transmembrane region
PF07155 (HMM): ECF-type riboflavin transporter, S component
PF09605 (HMM): putative bacterial integral membrane protein
PF06177 (HMM): QueT transporter
PF12822 (HMM): putative ECF-type cofactor transporter S component
PF09515 (HMM): thiamine transporter, ThiA/YuaJ family
TIGR02357 (HMM): energy-coupled thiamine transporter ThiT
TIGR02359 (HMM): energy coupling factor transporter S component ThiW
PF09819 (HMM): putative ECF-type cofactor transporter S component, YkoE family
TIGR04002 (HMM): TIGR04002 family protein
TIGR00123 (HMM): cobalamin biosynthesis protein CbiM
TIGR04522 (HMM): putative energy coupling factor transporter S component
ECF transporter T componentECF_TYESPF02361 (HMM): energy coupling factor transporter T component

Parent Properties

Sibling Properties
GenProp0179protein transport
GenProp0180small molecule transport
GenProp0489F-type conjugation system
GenProp0649heterocyst-related ABC exporter DevBCA
GenProp0821putative Na:solute symporter two-gene cassette
GenProp0857anchored repeat-class ABC transporter, P. acnes type
GenProp0895alcohol ABC transporter, PedABC-type
GenProp0941TonB-dependent nutrient uptake pairs, RagAB/SusCD type