Accession | GenProp0895 |
Name | alcohol ABC transporter, PedABC-type |
Type | SYSTEM |
Description | A conserved four-gene operon, found regularly in genomes with PQQ biosynthesis and with PQQ-dependent enzymes for catabolism of various alcohols, appears to represent an alcohol import ABC transporter. This conclusion is based partly on recognizing one member of the operon as a likely periplasmic substrate-binding protein. An earlier view (PMID:18177365) imagines this system to be an efflux transporter for removal of toxic intermediates during catabolism. |
JCVI Role | Carbohydrates, organic alcohols, and acids |
Parent Property | GenProp0071: transport
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Literature References | [ 1 ] Arias S, Olivera ER, Arcos M, Naharro G, Luengo JM Genetic analyses and molecular characterization of the pathways involved in the conversion of 2-phenylethylamine and 2-phenylethanol into phenylacetic acid in Pseudomonas putida U. Environ Microbiol. 2008 Feb;10(2):413-32. Epub 2007 Dec 27. PMID 18177365 |
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Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
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alcohol ABC transporter, substrate-binding subunit | PQQbind | YES | TIGR03863 (HMM): ABC transporter, substrate binding protein, PQQ-dependent alcohol dehydrogenase system | |
alcohol ABC transporter, beta-propeller protein | PQQpedA | YES | TIGR03866 (HMM): PQQ-dependent catabolism-associated beta-propeller protein | |
alcohol ABC transporter, ATP-binding subunit | PQQpedB | YES | TIGR03864 (HMM): ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system | |
alcohol ABC transporter, permease subunit | PQQpedC | YES | TIGR03861 (HMM): alcohol ABC transporter, permease protein | |