Genome Property Definition Page

Name1-acylglycerol-3-phosphate biosynthesis, PlsX/Y pathway
DescriptionThis two-enzyme pathway for 1-acylglycerol-3-phosphate biosynthesis can replace the enzyme glycerol-3-phosphate O-acyltransferase ( of E. coli, and is more widely distributed. PlsX synthesizes the acylphosphate from an acyl group on a carrier (CoA or acyl carrier protein), and PlsY (YgiH, YneS) transfers the acyl group to glycerol-3-phosphate.
JCVI RoleBiosynthesis
Parent PropertyGenProp0838: lipid biosynthesis
Literature References
[ 1 ] Yoshimura M, Oshima T, Ogasawara N   Involvement of the YneS/YgiH and PlsX proteins in phospholipid biosynthesis in both Bacillus subtilis and Escherichia coli.   BMC Microbiol. 2007 Jul 24;7:69.  PMID 17645809
Gene Ontology TermGO:0006654: phosphatidic acid biosynthetic process (biological_process)

Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
plsXplsXYESTIGR00182 (HMM): fatty acid/phospholipid synthesis protein PlsXGO:0006654: phosphatidic acid biosynthetic process
acylphosphate:glycerol 3-phosphate acyltransferaseplsYYESTIGR00023 (HMM): acyl-phosphate glycerol 3-phosphate acyltransferaseGO:0006654: phosphatidic acid biosynthetic process

Parent Properties
GenProp0838lipid biosynthesis

Sibling Properties
GenProp0046IPP biosynthesis
GenProp0136ubiquinone biosynthesis from chorismate, aerobic
GenProp0297lipopolysaccharide biosynthesis
GenProp0299fatty acid biosynthesis
GenProp0758lycopene biosynthesis from IPP
GenProp0761hopanoid lipid biosynthesis
GenProp0836menaquinone biosynthesis