Genome Property Definition Page
Accession | GenProp0640 | |
Name | xanthine dehydrogenase | |
Type | SYSTEM | |
Description | Xanthine dehydrogenase is a molydbopterin-containing enzyme. It converts xanthine, from the purine pool, to urate, which is subsequently degraded. In bacteria, the enzyme usually is encoded as a small subunit, XdhA, that contains FAD and 2Fe2S cofactors and a large subunit, XdhB, that contains the molybdopterin cofactor. The accessory protein XdhC is usually but not always encoded next to the XdhAB gene pair. | |
JCVI Role | Other | |
Parent Property | GenProp0817: nucleotide catabolism/utilization pathways | |
Literature References |
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Components
Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
---|---|---|---|---|
xanthine dehydrogenase, 2Fe2S/FAD subunit | xdhA | YES | TIGR02963 (HMM): xanthine dehydrogenase, small subunit | |
xanthine dehydrogenase, molybdopterin subunit | xdhB | YES | TIGR02965 (HMM): xanthine dehydrogenase, molybdopterin binding subunit | |
xanthine dehydrogenase accessory protein XdhC | xdhC | YES | TIGR02964 (HMM): xanthine dehydrogenase accessory protein XdhC |
Parent Properties
Accession | Name |
---|---|
GenProp0817 | nucleotide catabolism/utilization pathways |
Sibling Properties
Accession | Name |
---|---|
GenProp0696 | xanthine utilization as a source of guanine-monophosphate (GMP) |
GenProp0700 | purine catabolism via urate, xanthine and allantoin |
GenProp0705 | xanthine dehydrogenase, bacillus type (pucABCDE) |
GenProp0813 | pyrimidine utilization operon, RutABCDEFGR |