• Genome Properties List
• Top Level Genome Properties

Genome Property Definition Page

Accession	GenProp1095
Name	exodeoxyribonuclease VII
Type	SYSTEM
Description	Exonuclease VII, consisting of a large subunit XseA and small subunit XseB, hydrolyzes single-stranded DNA. It acts in DNA mismatch repair and homologous recombination.
JCVI Role	DNA replication, recombination, and repair
Parent Property	GenProp0116: DNA metabolism
Literature References	[ 1 ]Poleszak K, Kaminska KH, Dunin-Horkawicz S, Lupas A, Skowronek KJ, Bujnicki JM  Delineation of structural domains and identification of functionally important residues in DNA repair enzyme exonuclease VII.  Nucleic Acids Res. 2012 Sep;40(16):8163-74. doi: 10.1093/nar/gks547.  PMID 22718974 [ 2 ]Larrea AA, Pedroso IM, Malhotra A, Myers RS  Identification of two conserved aspartic acid residues required for DNA digestion by a novel thermophilic Exonuclease VII in Thermotoga maritima.  Nucleic Acids Res. 2008 Oct;36(18):5992-6003. doi: 10.1093/nar/gkn588.  PMID 18812402

Components

Step Name	Step Num	Required	Evidence (Method)	Evidence Go Terms
exodeoxyribonuclease VII large subunit	XseA	YES	TIGR00237 (HMM): exodeoxyribonuclease VII, large subunit
exodeoxyribonuclease VII small subunit	XseB	YES	PF02609 (HMM): exodeoxyribonuclease VII, small subunit TIGR01280 (HMM): exodeoxyribonuclease VII, small subunit

Parent Properties

Accession	Name
GenProp0116	DNA metabolism

Sibling Properties

Accession	Name
GenProp0115	DNA repair
GenProp0198	ruvABC Holliday junction complex
GenProp0263	DNA polymerase III, bacterial
GenProp0455	restriction enzyme system, type I
GenProp0487	repABC-type alpha-proteobacterial replicon(s)
GenProp0650	type II restriction system, Alw26I/Eco31I/Esp3I family
GenProp0701	DNA sulfur modification system dnd
GenProp0806	replication initiation, bacterial
GenProp0977	DNA ligase/helicase system
GenProp1081	replication restart, PriA/PriB primosome pathway