Genome Property Definition Page

Nametoxin-antitoxin system, type I
DescriptionIn a type I toxin-antitoxin system, the toxin is a small peptide and the antitoxin is an antisense RNA. This arrangement contrast with type 2 systems, in which both toxin and antidote are small proteins.
JCVI RoleOther
Parent PropertyGenProp0066: selfish genetic elements
Literature References
[ 1 ]Brantl S  Bacterial type I toxin-antitoxin systems.  RNA Biol. 2012 Dec 1;9(12):1488-90. doi: 10.4161/rna.23045. Epub 2012 Dec 1.  PMID 23324552

Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
antisense RNAantisenNO
toxic peptide, type I toxin-antitoxin systemtoxinYESTIGR04459 (HMM): type I toxin-antitoxin system toxin TisB
PF13939 (HMM): toxin TisB, type I toxin-antitoxin system
PF13940 (HMM): toxin Ldr, type I toxin-antitoxin system
PF13955 (HMM): toxin Fst, type I toxin-antitoxin system
PF13956 (HMM): toxin Ibs, type I toxin-antitoxin system
PF08845 (HMM): toxin SymE, type I toxin-antitoxin system

Parent Properties
GenProp0066selfish genetic elements

Sibling Properties
GenProp0009integrative genetic element
GenProp0024group I intron
GenProp0025group II intron
GenProp0050prophage regions
GenProp0208phage: major features
GenProp0321toxin-antitoxin system, type II
GenProp0476protein-coding palindromic elements
GenProp1092toxin-antitoxin system, type III