Genome Property Definition Page

NameFirmicutes/Treponema mobile radical SAM system
DescriptionThis Genome Property is a cassette of two tandem radical SAM enzymes of unknown function, usually accompanied by a MarR family transcriptional regulator. Species with the system include both members of the genus Treponema from the human oral microbiome and from the phylum Firmicutes (class Clostridia) from gut microbiome. Sequence identity for enzymes spanning this taxonomic divide can exceed 95 percent, certain to indicate lateral gene transfer.
Parent PropertyGenProp0475: Unknown biological process

Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
mobile rSAM pair MarR family regulatorFT_MarRYESTIGR04472 (HMM): mobile rSAM pair MarR family regulator
radical SAM mobile pair protein AFTsam1YESTIGR04471 (HMM): radical SAM mobile pair protein A
radical SAM mobile pair protein BFTsam2YESTIGR04470 (HMM): radical SAM mobile pair protein B

Parent Properties
GenProp0475Unknown biological process

Sibling Properties
GenProp0470sporadically distributed four-gene operon
GenProp0471uncharacterized gene pair TIGR02683/TIGR02684
GenProp0472uncharacterized gene pair TIGR02687/TIGR02688
GenProp0627gene pair involved in iron and oxygen metabolism
GenProp0665peptide chain release operon, RctB-like/PrfH
GenProp0751Acidobacterial ADOP/PadR gene pairs
GenProp0790sporadic pair TIGR03545/TIGR03546
GenProp0798Enterococcus/Aeromonas extended locus
GenProp0830integral membrane mystery pair
GenProp0854ParB-rel/ThiF-rel cassette PRTRC
GenProp0868uncharacterized protein pair with twin-arg and repeat
GenProp0894Actinobacterial uncharacterized trio
GenProp0916radical SAM/uncharacterized protein TIGR03936 system
GenProp0940metallo-mystery pair
GenProp0959radical SAM/uncharacterized protein TIGR04002 system
GenProp0965YedE/YedF selenium handling system
GenProp1063Memo/AMMECR1/rSAM family trio system
GenProp1066uncharacterized cassette GAK (Grasp, Amphipathic, Kinase)