Genome Property Definition Page

NameCRISPR system, PreFran subtype
DescriptionCRISPR repeats are by definition Clustered Regularly Interspaced Short Palindromic Repeats. The repeats vary in size from 24 to 48 bp, interspaced by similarly sized non-repetitive sequences. These spacers often are derived from phage and other exogenous DNA, are transcribed into RNA, and confer resistance to those same phage. Several CRISPR-associated sequences (cas genes) are nearly as widespread as CRISPR itself and nearly always are found near repeat loci. Others represent minor cas genes that serve as markers for specific subtypes of CRISPR/cas system, each with characteristic cas gene makeup, repeat structure, and spacer length. The PreFran subtype is found in multiple reference genomes of Prevotella and Francisella, and found also in several additional species. It has a single long protein, Cpf1 (Cas protein 1 of PreFran subtype), in addition to Cas4, Cas1, and Cas2. The typical repeat has length 36.
Parent PropertyGenProp0021: CRISPR region

Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
Cas1, PreFran subtypeCas1YESTIGR04329 (HMM): CRISPR-associated endonuclease Cas1, subtype PREFRAN
Cas2Cas2YESTIGR01573 (HMM-CLUST): CRISPR-associated endonuclease Cas2
Cas4, PreFran subtypeCas4YESTIGR04328 (HMM): CRISPR-associated protein Cas4, subtype PREFRAN
CRISPR-associated protein Cpf1Cpf1YESTIGR04330 (HMM): CRISPR-associated protein Cpf1, subtype PREFRAN

Parent Properties
GenProp0021CRISPR region

Sibling Properties
GenProp0310CRISPR system, I-F/Ypest subtype
GenProp0313CRISPR system, I-C/Dvulg subtype
GenProp0314CRISPR system, II/Nmeni subtype
GenProp0315CRISPR system, I-E/Ecoli subtype
GenProp0316CRISPR system, III-B/RAMP module subtype
GenProp0317CRISPR system, I-B subtype, Tneap branch
GenProp0318CRISPR system, III-A/Mtube subtype
GenProp0319CRISPR system, I-A/Apern subtype
GenProp0320CRISPR system, I-B subtype, Hmari branch
GenProp0469CRISPR system, Dpsyc subtype
GenProp0670CRISPR system, Aferr subtype
GenProp0685CRISPR system, I-D/Cyano subtype
GenProp0768CRISPR system, Pging subtype
GenProp0922CRISPR system, Myxan subtype