Genome Property Definition Page
| Accession | GenProp1058 |
| Name | 2,3-dihydroxybenzoate biosynthesis |
| Type | PATHWAY |
| Description | 2,3-Dihydroxybenzoate is made in three steps from chorismate by the action of enzymes 5.4.4.2, 3.3.2.1, and 1.3.1.28. It can then be activated by (2,3-dihydroxybenzoyl)adenylate synthase (EC 2.7.7.58) to become a substrate for nonribosomal peptide synthases (NRPS) such as those that make catecholate siderophores. |
Components
| Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
|---|---|---|---|---|
| 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase | dhbA | YES | TIGR04316 (HMM): 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase | |
| isochorismatase | dhbB | YES | PF00857 (HMM): isochorismatase family protein | |
| isochorismate synthase | dhbC | YES | TIGR00543 (HMM): isochorismate synthase |