Genome Property Definition Page

NameO157(Ec) antigen biosynthesis
DescriptionThe E. coli O157 antigen consists of a repeating linear tetramer with the structure [->2)aDRha4NAc(1->3)aLFuc(1->4)bDGlc(1->3)aDGalNAc(1->].
Literature References
[ 1 ]Perry MB, MacLean L, Griffith DW  Structure of the O-chain polysaccharide of the phenol-phase soluble lipopolysaccharide of Escherichia coli 0:157:H7.  Biochem Cell Biol. 1986 Jan;64(1):21-8.  PMID 3008786
Web ReferencesECODAB_O157

Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
source of GDP-L-fucoseL-FucYESGenProp1024 (GENPROP): GDP-L-fucose biosynthesis from GDP-4-keto-6-deoxy-D-mannose
source of GDP-4-acetamido-D-rhamnoseRha4NAcYESGenProp1027 (GENPROP): GDP-4-acetamido-D-rhamnose (D-Rha4NAc) biosynthesis from D-perosamine
bDGlc(1->3)aDGalNAc transferaseWbdNYES2881 (RULE_BASE)
glycosyl transferase WbdOWbdOYES2883 (RULE_BASE)
glycosyl transferase WbdPWbdPYES2885 (RULE_BASE)
O157(Ec)-specific flippase wzxwzx157YES2884 (RULE_BASE)
O157(Ec)-specific polymerase wzywzy157YES2882 (RULE_BASE)