Genome Property Definition Page
| Accession | GenProp0932 |
| Name | O104(Ec) antigen biosynthesis |
| Type | METAPATH |
| Description | The O104 O-antigen is observed in E. coli strain 55989 and other EHEC strains. It consists of repeating of [->4)-a-D-Gal-(1->4)-a-Neu5,7,9Ac3-(2->3)-b-D-Gal-(1->3)b-D-GalNAc-(1-] units. The NeuABCD cassette for the biosynthesis of CMP-Neu5Ac is observed within the O-antigen cluster. |
| Parent Property | GenProp0913: E. coli O-antigen monomer biosynthesis clusters |
Components
| Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
|---|---|---|---|---|
| source of CMP-Neu5Ac | Neu5Ac | YES | GenProp0793 (GENPROP): CMP-N-acetylneuraminate biosynthesis from UDP-N-acetylglucosamine | |
| regulatory protein GalF | galF | YES | TIGR01105 (HMM-CLUST): regulatory protein GalF | |
| clustered gnd enzyme | gnd | NO | TIGR00873 (HMM-CLUST): 6-phosphogluconate dehydrogenase (decarboxylating) | |
| source of UDP-GalNAc | gne | YES | 2732 (RULE_BASE) | |
| a-Neu5Ac-(2->3)-b-D-Gal transferase | wbwA | YES | 2737 (RULE_BASE) | |
| a-D-Gal-(1->4)-a-Neu5Ac transferase | wbwB | YES | 2739 (RULE_BASE) | |
| b-D-Gal-(1->3)-b-D-GalNAc transferase | wbwC | YES | 2741 (RULE_BASE) | |
| O104-antigen specific transporter (flippase) | wzx104 | YES | 2740 (RULE_BASE) | |
| O104-antigen-specific polymerase | wzy104 | YES | 2738 (RULE_BASE) | |
| O104-antigen specific chain length determinant protein | wzz104 | NO | PF02706 (HMM-CLUST): chain length determinant protein |
Parent Properties
| Accession | Name |
|---|---|
| GenProp0913 | E. coli O-antigen monomer biosynthesis clusters |
Sibling Properties
| Accession | Name |
|---|---|
| GenProp0947 | O55(Ec) antigen biosynthesis |
| GenProp0949 | O111(Ec) antigen biosynthesis |
| GenProp0953 | O103(Ec) antigen biosynthesis |
| GenProp0963 | O2(Ec) antigen biosynthesis |
| GenProp1014 | O5(Ec) antigen biosynthesis |
| GenProp1018 | O8(Ec) antigen biosynthesis |
| GenProp1042 | O128(Ec) antigen biosynthesis |