Genome Property Definition Page
Accession | GenProp0923 | |
Name | mycothiol system | |
Type | SYSTEM | |
Description | Mycothiol is a glutathione analog common in the Actinobacteria, but not found elsewhere. This Genome Property provides a higher-level view of mycothiol metabolism that includes its synthesis (GenProp0753), the regeneration of mycothiol from mycothione (its disulfide-bonded dimer) by NADPH-dependent reduction, and a guild of mycothiol-dependent enzymes, the discovery of which is incomplete. | |
Parent Property | GenProp0075: protein modification, prosthetic groups and cofactors | |
Literature References |
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Gene Ontology Term | GO:0010126: mycothiol metabolic process (biological_process) |
Components
Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
---|---|---|---|---|
anti-sigma-R factor RsrA | antisig | YES | TIGR03988 (HMM): mycothiol system anti-sigma-R factor | |
mycothione reductase | disulf | YES | TIGR03452 (HMM): mycothione reductase | GO:0010126: mycothiol metabolic process |
mycothiol-dependent enzyme | myc_use | YES | TIGR03446 (HMM): mycothiol conjugate amidase Mca TIGR03451 (HMM): S-(hydroxymethyl)mycothiol dehydrogenase | GO:0010126: mycothiol metabolic process |
mycothiol biosynthesis | synth | YES | GenProp0753 (GENPROP): mycothiol biosynthesis |
Parent Properties
Accession | Name |
---|---|
GenProp0075 | protein modification, prosthetic groups and cofactors |
Sibling Properties
Accession | Name |
---|---|
GenProp0002 | coenzyme F420 utilization |
GenProp0016 | selenocysteine system |
GenProp0061 | lipoprotein system lgt/lsp/lnt |
GenProp0127 | Tat (Sec-independent) protein export |
GenProp0284 | cobalamin-utilizing enzymes |
GenProp0295 | prokaryotic N-terminal cleavage/methylation, type IV pilin-like |
GenProp0726 | selenium-dependent molybdenum hydroxylase system |
GenProp0745 | lipoyl-protein attachment |
GenProp0860 | tryptophan tryptophylquinone modification of methylamine dehydrogenase |
GenProp0918 | anaerobic sulfatase/maturase system |
GenProp0933 | bacillithiol utilization |
GenProp0938 | glycine radical enzyme system, YjjI/YjjW pair |
GenProp0943 | pyruvate formate-lyase system |