Genome Property Definition Page
| Accession | GenProp0912 |
| Name | Leptospira exopolysaccharide biosynthesis clusters |
| Type | GUILD |
Components
| Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
|---|---|---|---|---|
| sugar activating enzymes: nucleotidyltransferases, cytidyltransferases, kinases | activ | NO | PF02348 (HMM-CLUST): cytidylyltransferase PF00483 (HMM-CLUST): nucleotidyl transferase TIGR01207 (HMM-CLUST): glucose-1-phosphate thymidylyltransferase PF00294 (HMM-CLUST): carbohydrate kinase, pfkB family | |
| glycosyltransferases | glyctr | YES | PF00535 (HMM-CLUST): glycosyltransferase, group 2 family PF00534 (HMM-CLUST): glycosyltransferase, group 1 family | |
| sugar isomerizatation and epimerization enzymes | isom | NO | TIGR00236 (HMM-CLUST): UDP-N-acetylglucosamine 2-epimerase PF05523 (HMM-CLUST): WxcM-like, C-terminal TIGR01221 (HMM-CLUST): dTDP-4-dehydrorhamnose 3,5-epimerase PF02350 (HMM-CLUST): UDP-N-acetylglucosamine 2-epimerase PF03275 (HMM-CLUST): UDP-galactopyranose mutase | |
| sugar ring modification enzymes: synthases, lyases, aldolases, lactonases | modif | NO | PF03102 (HMM-CLUST): NeuB family PF03328 (HMM-CLUST): HpcH/HpaI aldolase/citrate lyase family TIGR01198 (HMM-CLUST): 6-phosphogluconolactonase PF04055 (HMM-CLUST): radical SAM family | |
| other known EPS enzymes (from synteny) | other | NO | PF08889 (HMM-CLUST): WbqC-like protein family | |
| EPS biosynthesis priming polyprenyl glycosylphosphotransferase | prime | YES | TIGR03025 (HMM): exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase | |
| sugar redox enzymes: dehydrogenases, epimerase/dehydratases, oxidases, reductases | redox | NO | PF01370 (HMM-CLUST): NAD dependent epimerase/dehydratase family PF00465 (HMM-CLUST): alcohol dehydrogenase, iron-containing PF00107 (HMM-CLUST): oxidoreductase, zinc-binding dehydrogenase family PF01408 (HMM-CLUST): oxidoreductase family, NAD-binding Rossmann fold PF00106 (HMM-CLUST): oxidoreductase, short chain dehydrogenase/reductase family PF00248 (HMM-CLUST): oxidoreductase, aldo/keto reductase family PF00389 (HMM-CLUST): D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain PF01370 (HMM-CLUST): NAD dependent epimerase/dehydratase family PF01266 (HMM-CLUST): FAD dependent oxidoreductase | |
| transcriptional activators | regul | NO | MarR (PF01047) clustered (MANUAL) | |
| sugar-associated domain of unknown function | sugDUF | NO | PF01380 (HMM-CLUST): SIS domain | |
| sugar modification transferases: amino-, carbamoyl-, acetyl-, methyl-, amido- | transf | NO | PF02543 (HMM-CLUST): carbamoyltransferase PF01041 (HMM-CLUST): DegT/DnrJ/EryC1/StrS aminotransferase family PF08241 (HMM-CLUST): methyltransferase domain TIGR01444 (HMM-CLUST): methyltransferase, FkbM family TIGR03573 (HMM-CLUST): N-acetyl sugar amidotransferase TIGR01855 (HMM-CLUST): imidazole glycerol phosphate synthase, glutamine amidotransferase subunit TIGR03572 (HMM-CLUST): glycosyl amidation-associated protein WbuZ PF00202 (HMM-CLUST): aminotransferase, class III PF00583 (HMM-CLUST): acetyltransferase, GNAT family PF02388 (HMM-CLUST): FemAB family PF08242 (HMM-CLUST): methyltransferase domain PF00551 (HMM-CLUST): formyl transferase domain protein | |
| sugar trimming enzymes: phosphatases, deacetylases, esterases | trim | NO | PF00459 (HMM-CLUST): inositol monophosphatase family PF01522 (HMM-CLUST): polysaccharide deacetylase PF02585 (HMM-CLUST): N-acetylglucosaminylphosphatidylinositol deacetylase | |
| transposases | tspsase | NO | PF01548 (HMM-CLUST): transposase | |
| EPS biosynthesis wzx/wzy/wzz system | wz-xyz | YES | PF02706 (HMM): chain length determinant protein PF01943 (HMM): polysaccharide biosynthesis protein |