Accession | GenProp0908 |
Name | 2,3-diaminopropionic acid biosynthesis |
Type | PATHWAY |
Description | L-2,3-diaminopropionic acid (Dap) is an intermediate in the biosynthesis of a number of metabolites, such as the siderophore staphyloferrin B. Cheung, et al. (2009) cite their own unpublished results that SbnA and SbnB produce Dap. SbnA is a pyridoxal phosphate-dependent enzyme distantly related to diaminopropionate ammonia-lyase. SbnB shows homology to an NAD-dependent alanine dehydrogenase of Archaeoglobus fulgidus. The two occasionally occur as a fusion protein. |
Literature References | [ 1 ]Cheung J, Beasley FC, Liu S, Lajoie GA, Heinrichs DE Molecular characterization of staphyloferrin B biosynthesis in Staphylococcus aureus. Mol Microbiol. 2009 Nov;74(3):594-608. Epub 2009 Sep 22. PMID 19775248 |
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