• Genome Properties List
• Top Level Genome Properties

Genome Property Definition Page

Accession	GenProp0907
Name	poly-beta-1,6 N-acetyl-D-glucosamine system, PgaABCD type
Type	SYSTEM
Description	This property describes the biosynthesis and delivery of a polysaccharide adhesin based on poly-beta-1,6-N-acetyl-D-glucosamine, partially N-deacetylated, as the system occurs in Gram-negative bacteria with a requirement for transit across the outer membrane. A related system, termed PIA (polysaccharide intercellular adhesin), occurs in certain Gram-positive species.
JCVI Role	Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Parent Property	GenProp0186: storage and structural polymer biosynthesis
Literature References	[ 1 ]Itoh Y, Rice JD, Goller C, Pannuri A, Taylor J, Meisner J, Beveridge TJ, Preston JF 3rd, Romeo T  Roles of pgaABCD genes in synthesis, modification, and export of the Escherichia coli biofilm adhesin poly-beta-1,6-N-acetyl-D-glucosamine.  J Bacteriol. 2008 May;190(10):3670-80. Epub 2008 Mar 21.  PMID 18359807
Gene Ontology Term	GO:0015774: polysaccharide transport (biological_process) GO:0042710: biofilm formation (biological_process) GO:0042710: biofilm formation (biological_process) GO:0045226: extracellular polysaccharide biosynthetic process (biological_process)

Components

Step Name	Step Num	Required	Evidence (Method)	Evidence Go Terms
poly-beta-1,6 N-acetyl-D-glucosamine export porin	PgaA	YES	TIGR03939 (HMM): poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA	GO:0015774: polysaccharide transport GO:0042710: biofilm formation
poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase	PgaB	YES	TIGR03938 (HMM): poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB	GO:0045226: extracellular polysaccharide biosynthetic process GO:0042710: biofilm formation
poly-beta-1,6 N-acetyl-D-glucosamine synthase	PgaC	YES	TIGR03937 (HMM): poly-beta-1,6 N-acetyl-D-glucosamine synthase	GO:0045226: extracellular polysaccharide biosynthetic process GO:0042710: biofilm formation
poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD	PgaD	YES	TIGR03940 (HMM): poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD	GO:0045226: extracellular polysaccharide biosynthetic process GO:0042710: biofilm formation

Parent Properties

Accession	Name
GenProp0186	storage and structural polymer biosynthesis

Sibling Properties

Accession	Name
GenProp0055	polyhydroxyalkanoic acids
GenProp0156	cyanophycin-like storage polymers
GenProp0158	peptidoglycan(murein) biosynthesis
GenProp0168	glycogen system
GenProp0183	dTDP-L-rhamnose biosynthesis from dTDP-4-dehydro-L-rhamnose
GenProp0297	lipopolysaccharide biosynthesis
GenProp0652	exopolysaccharide biosynthesis, exosortase A-associated
GenProp0655	exopolysaccharide biosynthesis, exosortase B-associated
GenProp0658	cellulose biosynthesis
GenProp0793	CMP-N-acetylneuraminate biosynthesis from UDP-N-acetylglucosamine
GenProp0822	poly(gamma-glutamic acid) biosynthesis
GenProp0906	poly-beta-1,6 N-acetyl-D-glucosamine system, IcaADBC type