Genome Property Definition Page

Nameproposed F420-0 transporter
DescriptionThis small clade of ABC-type transporters are found in Actinobacteria containing numerous genes requiring the coenzyme F420. This property was defined based on five such organisms, four of which are lacking all F420 biosynthetic capability save the final side-chain polyglutamate attachment step (via the gene cofE: TIGR01916). In Jonesia denitrificans DSM 20603 and marine actinobacterium PHSC20C1 this cassette is in an apparent operon with the cofE gene and, in PHSC20C1, also with a F420-dependent glucose-6-phosphate dehydrogenase (TIGR03554). Based on these observations we propose that this is an f420-0 (that is, F420 lacking only the polyglutamate tail) ABC transporter.

Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
proposed F420-0 transporter ATP-binding proteinATPaseYESTIGR03873 (HMM): proposed F420-0 ABC transporter, ATP-binding protein
proposed F420-0 periplasmic binding proteinperiYESTIGR03868 (HMM): proposed F420-0 ABC transporter, periplasmic F420-0 binding protein
proposed F420-0 permeasepermYESTIGR03869 (HMM): proposed F420-0 ABC transporter, permease protein