| Accession | GenProp0870 |
| Name | decarboxylation/antiport proton-motive cycle: lysine-cadaverine |
| Type | SYSTEM |
| Description | The decarboxylation of lysine to cadaverine consumes a proton. Exchange of lysine for cadaverine by an antiporter completes a cycle that effectively removes a cytosolic proton. Decarboxylation/antiporter systems for this and other (e.g. aspartate-alanine) substrate pairs can provide protection against acidic pH. |
| JCVI Role | Adaptations to atypical conditions |
| Parent Property | GenProp0873: ion-motive antiporter cycles
GenProp0874: response to acid (low pH) environment
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| Literature References | [ 1 ] Soksawatmaekhin W, Uemura T, Fukiwake N, Kashiwagi K, Igarashi K Identification of the cadaverine recognition site on the cadaverine-lysine antiporter CadB. J Biol Chem. 2006 Sep 29;281(39):29213-20. PMID 16877381
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| Gene Ontology Term | GO:0010248: establishment or maintenance of transmembrane electrochemical gradient (biological_process)
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