Genome Property Definition Page

Accession

GenProp0849

Name

quorum-sensing, Bacillus PlcR-PapR system

Type

SYSTEM

Description

Activity of the Bacillus cereus virulence transcriptional activator PlcR depends on binding to the C-terminal heptapeptide of PapR. PapR is exported, cleaved extracellularly by the NprB protease, and the active peptide imported by the oligopeptide permease system OppABCDF.

JCVI Role

Other

Parent Property

GenProp0074: virulence
GenProp0551: regulatory systems
GenProp1048: quorum-sensing, biofilm formation, and developmental systems

Literature References

[ 1 ] Bouillaut L, Perchat S, Arold S, Zorrilla S, Slamti L, Henry C, Gohar M, Declerck N, Lereclus D Molecular basis for group-specific activation of the virulence regulator PlcR by PapR heptapeptides. Nucleic Acids Res. 2008 Jun;36(11):3791-801. PMID 18492723

Gene Ontology Term

GO:0052100: intraspecies quorum sensing (biological_process)

Components

Step Name	Step Num	Required	Evidence (Method)	Evidence Go Terms
cell-cell signalling protein PapR	papR	YES	PF05968 (HMM): cell-cell signaling protein PapR	GO:0052100: intraspecies quorum sensing
global transcriptional regulator PlcR	plcR	YES	2403 (RULE_BASE)	GO:0052100: intraspecies quorum sensing

Parent Properties

Accession	Name
GenProp0074	virulence
GenProp0551	regulatory systems
GenProp1048	quorum-sensing, biofilm formation, and developmental systems

Sibling Properties

Accession	Name
GenProp0032	pathogen of plants
GenProp0049	spore formation
GenProp0051	urease
GenProp0052	type III secretion
GenProp0056	type IV pilus
GenProp0062	capsule
GenProp0154	intrinsic pathogen of animals
GenProp0648	phage shock protein regulon
GenProp0707	botulinum toxin system
GenProp0456	attenuation system: tryptophanase
GenProp0465	circadian clock system KaiABC
GenProp0762	chemotaxis response-regulator system
GenProp0652	exopolysaccharide biosynthesis, exosortase A-associated
GenProp0655	exopolysaccharide biosynthesis, exosortase B-associated
GenProp0658	cellulose biosynthesis
GenProp0757	quorum-sensing, autoinducer-2 system
GenProp1011	quorum-sensing system, cyclic peptide-mediated