Genome Property Definition Page
| Accession | GenProp0834 |
| Name | proteasome, bacterial |
| Type | SYSTEM |
| Description | The proteasome, a large complex formed of alpha and beta subunits, performs protein degradation in eukaryotes, archaea, and bacteria. This Genome Property describes a bacterial 20S proteasome that approximates being restricted to and universal in the Actinobacteria. Nearly all bacterial with this proteasomal system use pupylation to tag proteins as proteasomal targets. The HslVU system in many bacteria is related, with HslV homologous to the proteasome beta subunit, but that system is outside the scope of the archaeal-type bacterial 20S proteasome described here. |
| JCVI Role | Degradation of proteins, peptides, and glycopeptides |
| Parent Property | GenProp0301: protein degradation |
| Gene Ontology Term | GO:0010498: proteasomal protein catabolic process (biological_process) |
Components
| Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
|---|---|---|---|---|
| proteasome, alpha subunit | prcA | YES | TIGR03691 (HMM): proteasome, alpha subunit | GO:0010498: proteasomal protein catabolic process |
| proteasome, beta subunit | prcB | YES | TIGR03690 (HMM): proteasome, beta subunit | GO:0010498: proteasomal protein catabolic process |
Parent Properties
| Accession | Name |
|---|---|
| GenProp0301 | protein degradation |
Sibling Properties
| Accession | Name |
|---|---|
| GenProp0211 | tmRNA trans-translation system |
| GenProp0251 | clpXP degradation machine |
| GenProp0684 | FtsH/HflKC protease complex |
| GenProp0833 | proteasome-targeting modification by pupylation |
| GenProp0835 | ATP-dependent protease HslVU |