Accession | GenProp0829 |
Name | menaquinone biosynthesis via futalosine |
Type | PATHWAY |
Description | This pathway for the biosynthesis of menaquinone begins with chorismate, but otherwise is completely distinctive compared to the well-known E. coli pathway (GenProp0058). |
Parent Property | GenProp0836: menaquinone biosynthesis
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Literature References | [ 1 ] Hiratsuka T, Furihata K, Ishikawa J, Yamashita H, Itoh N, Seto H, Dairi T An alternative menaquinone biosynthetic pathway operating in microorganisms. Science. 2008 Sep 19;321(5896):1670-3. PMID 18801996 |
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Gene Ontology Term | GO:0009234: menaquinone biosynthetic process (biological_process)
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Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
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prenyltransferase | PT | YES | TIGR01475 (HMM): putative 4-hydroxybenzoate polyprenyltransferase | GO:0009234: menaquinone biosynthetic process
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futalosine synthase | futa_1 | YES | PF02621 (HMM): menaquinone biosynthesis protein | GO:0009234: menaquinone biosynthetic process
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futalosine hydrolase | futa_2 | YES | TIGR03664 (HMM): futalosine hydrolase | GO:0009234: menaquinone biosynthetic process
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de-hypoxanthine futalosine (DHFL) cyclase | futa_3 | YES | TIGR03699 (HMM): dehypoxanthine futalosine cyclase | GO:0009234: menaquinone biosynthetic process
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1,4-dihydroxy-6-naphthoate (DHN) synthase | futa_4 | YES | PF02642 (HMM): | GO:0009234: menaquinone biosynthetic process
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decarboxylase | futa_X | YES | TIGR03701 (HMM): menaquinone biosynthesis decarboxylase, SCO4490 family | GO:0009234: menaquinone biosynthetic process
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putative menaquinone biosynthesis protein, SCO4494 family | futa_Y | YES | TIGR03700 (HMM): putative menaquinone biosynthesis radical SAM enzyme, SCO4494 family | GO:0009234: menaquinone biosynthetic process
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