Genome Property Definition Page

Namemenaquinone biosynthesis via futalosine
DescriptionThis pathway for the biosynthesis of menaquinone begins with chorismate, but otherwise is completely distinctive compared to the well-known E. coli pathway (GenProp0058).
Parent PropertyGenProp0836: menaquinone biosynthesis
Literature References
[ 1 ] Hiratsuka T, Furihata K, Ishikawa J, Yamashita H, Itoh N, Seto H, Dairi T   An alternative menaquinone biosynthetic pathway operating in microorganisms.   Science. 2008 Sep 19;321(5896):1670-3.  PMID 18801996
Gene Ontology TermGO:0009234: menaquinone biosynthetic process (biological_process)

Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
prenyltransferasePTYESTIGR01475 (HMM): putative 4-hydroxybenzoate polyprenyltransferaseGO:0009234: menaquinone biosynthetic process
futalosine synthasefuta_1YESPF02621 (HMM): menaquinone biosynthesis proteinGO:0009234: menaquinone biosynthetic process
futalosine hydrolasefuta_2YESTIGR03664 (HMM): futalosine hydrolaseGO:0009234: menaquinone biosynthetic process
de-hypoxanthine futalosine (DHFL) cyclasefuta_3YESTIGR03699 (HMM): dehypoxanthine futalosine cyclaseGO:0009234: menaquinone biosynthetic process
1,4-dihydroxy-6-naphthoate (DHN) synthasefuta_4YESPF02642 (HMM): GO:0009234: menaquinone biosynthetic process
decarboxylasefuta_XYESTIGR03701 (HMM): menaquinone biosynthesis decarboxylase, SCO4490 familyGO:0009234: menaquinone biosynthetic process
putative menaquinone biosynthesis protein, SCO4494 familyfuta_YYESTIGR03700 (HMM): putative menaquinone biosynthesis radical SAM enzyme, SCO4494 familyGO:0009234: menaquinone biosynthetic process

Parent Properties
GenProp0836menaquinone biosynthesis

Sibling Properties
GenProp0058menaquinone biosynthesis via SEPHCHC