Genome Property Definition Page
| Accession | GenProp0784 |
| Name | carbon fixation via 3-hydroxypropionate and 4-hydroxybutyrate |
| Type | PATHWAY |
| Description | This fifth discovered carbon assimilation pathway is found mainly in Archaea and consists of a cycle of 16 steps in which two molecules of carbonate are consumed and one molecule of acetyl-CoA is produced. The acetyl-CoA pruduced is further condensed with another molecule of carbon dioxide to form pyruvate. To the point of pyruvate four molecules of ATP are converted to two ADPs and two AMPs, and five molecules NADPH and two molecules of ferredoxin are oxidized while one molecule of NAD+ is reduced. |
| Parent Property | GenProp0865: carbon fixation |
Components
| Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
|---|---|---|---|---|
| acetyl-CoA carboxylase | 1 | YES | ||
| succinyl-CoA reductase (NADPH) | 10 | YES | ||
| succinate semialdehyde reductase (NADPH) | 11 | YES | ||
| 4-hydroxybutyryl-CoA synthetase (AMP-forming) | 12 | YES | ||
| 4-hydroxybutyryl-CoA dehydratase | 13 | YES | ||
| crotonyl-CoA hydratase | 14 | YES | ||
| 3-hydroxybutyryl-CoA dehydrogenase (NAD+) | 15 | YES | ||
| acetoacetyl-CoA beta-ketothiolase | 16 | YES | ||
| pyruvate synthase | 17 | NO | ||
| acetyl-CoA carboxylase, subunit b | 1b | YES | ||
| acetyl-CoA carboxylase, subunit c | 1c | YES | ||
| malonyl-CoA reductase | 2 | YES | ||
| malonate semialdehyde reductase (NADPH) | 3 | YES | ||
| 3-hydroxypropionyl-CoA synthetase (AMP-forming) | 4 | YES | ||
| 3-hydroxypropionyl-CoA dehydratase | 5 | YES | ||
| acryloyl-CoA reductase (NADPH) | 6 | YES | ||
| propionyl-CoA carboxylase | 7 | YES | ||
| propionyl-CoA carboxylase, subunit b | 7b | YES | ||
| propionyl-CoA carboxylase, subunit c | 7c | YES | ||
| methylmalonyl-CoA epimerase | 8 | YES | ||
| methylmalonyl-CoA mutase | 9 | YES | ||
| methylmalonyl-CoA mutase, subunit b | 9b | YES |
Parent Properties
| Accession | Name |
|---|---|
| GenProp0865 | carbon fixation |
Sibling Properties
| Accession | Name |
|---|---|
| GenProp0035 | Calvin cycle |