Genome Property Definition Page

Accession

GenProp0783

Name

petrobactin biosynthesis

Type

SYSTEM

Description

Petrobactin was discovered in the oil-degrading marine bacterium Marinobacter hydrocarbonoclasticus. It has also been called anthrachelin. Bacillus anthracis makes petrobactin and bacillobactin.

JCVI Role

Siderophores

Parent Property

GenProp0770: siderophore biosynthesis

Literature References

[ 1 ] Pfleger BF, Lee JY, Somu RV, Aldrich CC, Hanna PC, Sherman DH   Characterization and analysis of early enzymes for petrobactin biosynthesis in Bacillus anthracis.   Biochemistry. 2007 Apr 3;46(13):4147-57.  PMID 17346033
[ 2 ] Oves-Costales D, Kadi N, Fogg MJ, Song L, Wilson KS, Challis GL   Enzymatic logic of anthrax stealth siderophore biosynthesis: AsbA catalyzes ATP-dependent condensation of citric acid and spermidine.   J Am Chem Soc. 2007 Jul 11;129(27):8416-7.  PMID 17579415
[ 3 ] Lee JY, Janes BK, Passalacqua KD, Pfleger BF, Bergman NH, Liu H, Hakansson K, Somu RV, Aldrich CC, Cendrowski S, Hanna PC, Sherman DH   Biosynthetic analysis of the petrobactin siderophore pathway from Bacillus anthracis.   J Bacteriol. 2007 Mar;189(5):1698-710.  PMID 17189355

Gene Ontology Term

GO:0019290: siderophore biosynthetic process (biological_process)

Components

Step Name	Step Num	Required	Evidence (Method)	Evidence Go Terms
petrobactin biosynthesis enzyme AsbA	AsbA	YES	2257 (RULE_BASE)	GO:0019290: siderophore biosynthetic process
petrobactin biosynthesis enzyme AsbB	AsbB	YES	2256 (RULE_BASE)	GO:0019290: siderophore biosynthetic process
3,4-dihydroxybenzoic acid-AMP ligase AsbC	AsbC	YES	2258 (RULE_BASE)	GO:0019290: siderophore biosynthetic process
petrobactin biosynthesis aryl carrier protein AsbD	AsbD	YES	2259 (RULE_BASE)	GO:0019290: siderophore biosynthetic process
petrobactin biosynthesis enzyme AsbE	AsbE	YES	2260 (RULE_BASE)	GO:0019290: siderophore biosynthetic process
petrobactin biosynthesis protein AsbF	AsbF	YES	2261 (RULE_BASE)	GO:0019290: siderophore biosynthetic process

Parent Properties

Accession	Name
GenProp0770	siderophore biosynthesis

Sibling Properties

Accession	Name
GenProp0771	enterobactin (enterochelin) biosynthesis
GenProp0772	yersiniabactin biosynthesis
GenProp0773	aerobactin biosynthesis
GenProp0775	mycobactin biosynthesis
GenProp0776	pyochelin biosynthesis
GenProp0777	staphylobactin biosynthesis