| Accession | GenProp0766 |
| Name | anhydro-N-acetylmuramic acid to N-acetylglucosamine-phosphate |
| Type | PATHWAY |
| Description | Components of the bacterial murein cell wall, including 1,6-anhydro-N-acetylmuramic acid (anhMurNAc), N-acetyl-D-glucosamine (GlcNAc), D-alanine, and murein tripeptide are released during in murein recycling as bacteria grow. Pathways exist to recycle these components for the biosynthesis of new cell wall. This pathway describes a two-enzyme pathway for converting anhMurNAc into N-acetylglucosamine-phosphate. |
| JCVI Role | Biosynthesis and degradation of murein sacculus and peptidoglycan |
| Parent Property | GenProp0795: carbohydrate biosynthesis
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| Literature References | [ 1 ] Uehara T, Suefuji K, Valbuena N, Meehan B, Donegan M, Park JT Recycling of the anhydro-N-acetylmuramic acid derived from cell wall murein involves a two-step conversion to N-acetylglucosamine-phosphate. J Bacteriol. 2005 Jun;187(11):3643-9. PMID 15901686
[ 2 ] Uehara T, Suefuji K, Jaeger T, Mayer C, Park JT MurQ Etherase is required by Escherichia coli in order to metabolize anhydro-N-acetylmuramic acid obtained either from the environment or from its own cell wall. J Bacteriol. 2006 Feb;188(4):1660-2. PMID 16452451
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| Gene Ontology Term | GO:0009254: peptidoglycan turnover (biological_process)
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