Genome Property Definition Page

Nameadenosine monophosphate (AMP) biosynthesis from inosine monophosphate (IMP)
DescriptionThis two-step pathway in purine biosynthesis begins with IMP (inosine monophosphate), a branch point in purine de novo biosynthesis. Adenylosuccinate synthetase (EC, product of the PurA gene, catalyzes the first committed step to AMP. Adenylosuccinate lyase (EC, product of the purB gene, catalyzes the second and final step, but it also catalyzes the eighth step in IMP biosynthesis.
JCVI RolePurine ribonucleotide biosynthesis
Parent PropertyGenProp0185: nucleotide biosynthesis
Gene Ontology TermGO:0006167: AMP biosynthetic process (biological_process)

Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
adenylosuccinate synthetasepurAYESTIGR00184 (HMM): adenylosuccinate synthaseGO:0006167: AMP biosynthetic process
adenylosuccinate lyasepurBYESTIGR00928 (HMM): adenylosuccinate lyaseGO:0006167: AMP biosynthetic process

Parent Properties
GenProp0185nucleotide biosynthesis

Sibling Properties
GenProp0110purine (inosine-5'-phosphate) biosynthesis from ribose-5-phosphate
GenProp0187pyrimidine (uridine-5'-phosphate) de novo biosynthesis
GenProp0673ribulose monophosphate pathway
GenProp0696xanthine utilization as a source of guanine-monophosphate (GMP)
GenProp0697guanine monophosphate (GMP) biosynthesis from inosine monophosphate (IMP)