Genome Property Definition Page
Accession | GenProp0697 |
Name | guanine monophosphate (GMP) biosynthesis from inosine monophosphate (IMP) |
Type | PATHWAY |
Description | Inosine monophosphate (IMP) can be used as a source of guanosine monophosphate (GMP) via this pathway in which xanthosine monophosphate (XMP) is an intermediate. IMP may come from de novo biosynthesis (GenProp0110) or by the import of inosine derivatives. |
JCVI Role | Purine ribonucleotide biosynthesis |
Parent Property | GenProp0185: nucleotide biosynthesis |
Web References | KEGG: Purine Metabolism: GMP Biosynthesis |
Gene Ontology Term | GO:0006177: GMP biosynthetic process (biological_process) |
Components
Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
---|---|---|---|---|
GMP synthase, C-term | GuaA-C | YES | TIGR00884 (HMM): GMP synthase (glutamine-hydrolyzing), C-terminal domain | GO:0006177: GMP biosynthetic process |
GMP synthase, N-term | GuaA-N | YES | TIGR00888 (HMM): GMP synthase (glutamine-hydrolyzing), N-terminal domain | GO:0006177: GMP biosynthetic process |
inosine-5'-phosphate dehydrogenase | GuaB | YES | TIGR01302 (HMM): inosine-5'-monophosphate dehydrogenase | GO:0006177: GMP biosynthetic process |
Parent Properties
Accession | Name |
---|---|
GenProp0185 | nucleotide biosynthesis |
Sibling Properties
Accession | Name |
---|---|
GenProp0110 | purine (inosine-5'-phosphate) biosynthesis from ribose-5-phosphate |
GenProp0187 | pyrimidine (uridine-5'-phosphate) de novo biosynthesis |
GenProp0673 | ribulose monophosphate pathway |
GenProp0696 | xanthine utilization as a source of guanine-monophosphate (GMP) |
GenProp0747 | adenosine monophosphate (AMP) biosynthesis from inosine monophosphate (IMP) |