Genome Property Definition Page

Nameguanine monophosphate (GMP) biosynthesis from inosine monophosphate (IMP)
DescriptionInosine monophosphate (IMP) can be used as a source of guanosine monophosphate (GMP) via this pathway in which xanthosine monophosphate (XMP) is an intermediate. IMP may come from de novo biosynthesis (GenProp0110) or by the import of inosine derivatives.
JCVI RolePurine ribonucleotide biosynthesis
Parent PropertyGenProp0185: nucleotide biosynthesis
Web ReferencesKEGG: Purine Metabolism: GMP Biosynthesis
Gene Ontology TermGO:0006177: GMP biosynthetic process (biological_process)

Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
GMP synthase, C-termGuaA-CYESTIGR00884 (HMM): GMP synthase (glutamine-hydrolyzing), C-terminal domainGO:0006177: GMP biosynthetic process
GMP synthase, N-termGuaA-NYESTIGR00888 (HMM): GMP synthase (glutamine-hydrolyzing), N-terminal domainGO:0006177: GMP biosynthetic process
inosine-5'-phosphate dehydrogenaseGuaBYESTIGR01302 (HMM): inosine-5'-monophosphate dehydrogenaseGO:0006177: GMP biosynthetic process

Parent Properties
GenProp0185nucleotide biosynthesis

Sibling Properties
GenProp0110purine (inosine-5'-phosphate) biosynthesis from ribose-5-phosphate
GenProp0187pyrimidine (uridine-5'-phosphate) de novo biosynthesis
GenProp0673ribulose monophosphate pathway
GenProp0696xanthine utilization as a source of guanine-monophosphate (GMP)
GenProp0747adenosine monophosphate (AMP) biosynthesis from inosine monophosphate (IMP)