Genome Property Definition Page
Accession | GenProp0689 |
Name | glyoxalate conversion to phosphoglycerate |
Type | PATHWAY |
Description | Glyoxalate is a common intermediate produced by a number of catabolic and anapleurotic pathways, notably the breakdown for allantoate, proline and glycine and the glyoxalate shunt. This pathway is initiated by the incorporation of carbon dioxide utilizing the TPP-dependent enzyme, tartronate-semialdehyde synthase (aka glyoxalate carbo-ligase, gcl). Note that this is not a carbon-fixation pathway. For instance, in the case of allantoate catabolism, the production of glyoxalate also produces one or more molecules of carbon dioxide. Intermediates in this pathway (tartronate semialdehyde, and glycerate) may be diverted to other final products involved, for instance in covactor biosynthesis. Phosphoglycerate may be put to a large number of metabolic uses. |
JCVI Role | Other |
Parent Property | GenProp0072: central intermediary metabolism |
Components
Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
---|---|---|---|---|
glyoxalate carbo-ligase | gcl | YES | TIGR01504 (HMM): glyoxylate carboligase | |
glycerate kinase (2.7.1.31) | glxK | YES | GENE_CLUST (MANUAL) | |
tartronate semialdehyde reductase (1.1.1.60) | glxR | YES | TIGR01505 (HMM): 2-hydroxy-3-oxopropionate reductase | |
hydroxypyruvate isomerase | hyi | NO | TIGR03234 (HMM): hydroxypyruvate isomerase |
Parent Properties
Accession | Name |
---|---|
GenProp0072 | central intermediary metabolism |
Sibling Properties
Accession | Name |
---|---|
GenProp0031 | methane utilization |
GenProp0035 | Calvin cycle |
GenProp0118 | ornithine biosynthesis from glutamate, acetylated branch |
GenProp0120 | pentose phosphate cycle |
GenProp0143 | Leloir pathway (galactose/glucose interconversion) |
GenProp0196 | sulfur metabolism |
GenProp0202 | nitrogen metabolism |
GenProp0242 | phosphorus metabolism |
GenProp0478 | acetyl-CoA -- acetate interconversion via acetyl phosphate |
GenProp0479 | acetate -- acetyl-CoA interconversions |
GenProp0865 | carbon fixation |