Genome Property Definition Page
Accession | GenProp0677 | |
Name | queuosine (Q-tRNA) biosynthesis from preQ0 | |
Type | PATHWAY | |
Description | preQ0 (7-cyano-7-deazaguanine) is the last common intermediate in the biosyntheses of queuosine (in bacteria and eukarya) and archaeosine (in archaea). preQ0 is converted to queuosine by the action of at least four enzymes, two reductases, a tRNA(GUN) transferase and an adenosylmethionine ribosyl transferase-isomerase. | |
JCVI Role | tRNA and rRNA base modification | |
Parent Property | GenProp0819: RNA metabolism | |
Literature References |
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Gene Ontology Term | GO:0008616: queuosine biosynthetic process (biological_process) |
Components
Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
---|---|---|---|---|
preQ1 tRNA transferase | Q1trans | YES | TIGR00430 (HMM): tRNA-guanine transglycosylase | GO:0008616: queuosine biosynthetic process |
queuosine synthetase oxo-queuosine reductase | Qsynth | NO | ||
preQ1-tRNA adenosyl methionine ribosyl transferase isomerase | QueA | YES | TIGR00113 (HMM): S-adenosylmethionine:tRNA ribosyltransferase-isomerase | GO:0008616: queuosine biosynthetic process |
preQ0 reductase | QueF | YES | TIGR03138 (HMM): queuine synthase TIGR03139 (HMM): 7-cyano-7-deazaguanine reductase | GO:0008616: queuosine biosynthetic process GO:0008616: queuosine biosynthetic process |
epoxyqueuosine reductase | QueG | YES | TIGR00276 (HMM): epoxyqueuosine reductase | GO:0008616: queuosine biosynthetic process |
Parent Properties
Accession | Name |
---|---|
GenProp0819 | RNA metabolism |
Sibling Properties
Accession | Name |
---|---|
GenProp0258 | tRNA aminoacylation |
GenProp0262 | RNA polymerase, bacterial |
GenProp0482 | 6S RNA (eubacterial RNA polymerase regulator) |
GenProp0692 | selenouridine-containing tRNA |
GenProp0704 | tRNA U34 carboxymethylaminomethyl modification |
GenProp0898 | RNA ligase/unknown protein pair |
GenProp0948 | RNA repair, Hen1/Pnkp system |
GenProp1060 | tRNA N6-threonylcarbamoyladenosine modification |
GenProp1077 | tRNA(Pro) cmo5UGG modification |
GenProp1082 | 16S rRNA C1402 m(4)Cm modification |