Genome Property Definition Page
| Accession | GenProp0659 |
| Name | tryptophan degradation to anthranilate |
| Type | PATHWAY |
| Description | Tryptophan 2,3-dioxygenase (1.13.11.11) converts Trp to L-formylkynurenine. Arylformamidase (3.5.1.9) converts the product to L-kynurenine + formate. Kynureninase (3.7.1.3) converts L-kynurenine + H(2)O = anthranilate + L-alanine. |
| JCVI Role | Amino acids and amines |
| Parent Property | GenProp0734: amino acid catabolism |
Components
| Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
|---|---|---|---|---|
| tryptophan 2,3-dioxygenase | 2_3diox | YES | TIGR03036 (HMM): tryptophan 2,3-dioxygenase | |
| arylformamidase | formyl | YES | TIGR03035 (HMM): arylformamidase | |
| kynureninase | kynur | YES | TIGR01814 (HMM): kynureninase |
Parent Properties
| Accession | Name |
|---|---|
| GenProp0734 | amino acid catabolism |
Sibling Properties
| Accession | Name |
|---|---|
| GenProp0139 | degradation of tyrosine via homogentisate |
| GenProp0145 | histidine degradation to glutamate |
| GenProp0309 | arginine catabolism to glutamate via arginine succinyltransferase (AST) |
| GenProp0456 | attenuation system: tryptophanase |
| GenProp0639 | arginine degradation via citrulline, ATP-generating |