| Accession | GenProp0655 |
| Name | exopolysaccharide biosynthesis, exosortase B-associated |
| Type | SYSTEM |
| Description | At least 30 different bacterial species known so far have the
PEP-CTERM/exosortase system believed to process proteins analogously to the LPXTG/sortase system. Genes associated with this processing are found among exopolysaccharide biosynthesis genes, suggesting that PEP-CTERM proteins are part of this exopolysaccharide system, and therefore are likely to be transported across the outer membrane. This property represents a panel of exopolysaccharide biosynthesis genes where each belongs to a subfamily that marks its host gene as
carrying the PEP-CTERM/exopolysaccharide system.
This type 2 version of the system is found in Methylobacillus sp. strain 12S where it is embedded in a region for the biosynthesis of the exopolysaccharide mthanolan. |
| Parent Property | GenProp0186: storage and structural polymer biosynthesis
GenProp1048: quorum-sensing, biofilm formation, and developmental systems
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| Literature References | [ 1 ]Yoshida T, Ayabe Y, Yasunaga M, Usami Y, Habe H, Nojiri H, Omori T Genes involved in the synthesis of the exopolysaccharide methanolan by the obligate methylotroph Methylobacillus sp strain 12S. Microbiology. 2003 Feb;149(Pt 2):431-44. PMID 12624205
[ 2 ]Haft DH, Paulsen IT, Ward N, Selengut JD Exopolysaccharide-associated protein sorting in environmental organisms: the PEP-CTERM/EpsH system. Application of a novel phylogenetic profiling heuristic. BMC Biol. 2006 Aug 24;4(1):29. PMID 16930487
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| Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
|---|
| Transcriptional regulator EpsA | EpsA | NO | TIGR03020 (HMM): transcriptional regulator EpsA | |
| Undecaprenyl-phosphate glucose phosphotransferase EpsB | EpsB | YES | TIGR03023 (HMM-CLUST): undecaprenyl-phosphate glucose phosphotransferase | |
| polysaccharide export protein | EpsE | YES | TIGR03028 (HMM): polysaccharide export protein EpsE | |
| chain length determinant protein EpsF | EpsF | YES | TIGR03017 (HMM): chain length determinant protein EpsF | |
| protein tyrosine kinase EpsG | EpsG | YES | TIGR03029 (HMM): chain length determinant protein tyrosine kinase EpsG | |
| exosortase 2 | EpsH-2 | YES | TIGR03113 (HMM): exosortase B | |
| EpsL protein | EpsL | YES | TIGR03014 (HMM): exopolysaccharide biosynthesis operon protein EpsL | |
