Genome Property Definition Page
| Accession | GenProp0650 |
| Name | type II restriction system, Alw26I/Eco31I/Esp3I family |
| Type | SYSTEM |
| Description | This property consists of type II restriction system enzymes in the family of Alw26I, Eco31I, and Esp3I, which have similar recognition sites. The m5 cytosine DNA methyltransferase has an unusual cyclical perumutation of motifs, while the endonuclease shows only remote sequence similarity to other restriction endonucleases, and the m6 adenine DNA methyltransferase only remote similarity to other methyltransferases. The methyltransferases are tandem genes in some instances of this system, and a fusion protein in others. Three known recognition sequences for this family of restriction system are GTCTC, GGTCTC and CGTCTC. |
| JCVI Role | Restriction/modification |
| Parent Property | GenProp0116: DNA metabolism GenProp1067: Defense systems |
Components
| Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
|---|---|---|---|---|
| type II restriction endonuclease, Alw26I/Eco31I/Esp3I family | endonuc | YES | TIGR02986 (HMM): type II restriction endonuclease, Alw26I/Eco31I/Esp3I family | |
| adenine DNA methyltransferase | met_Ade | YES | TIGR02987 (HMM): type II restriction m6 adenine DNA methyltransferase, Alw26I/Eco31I/Esp3I family | |
| type II restriction m5 cytosine DNA methyltransferase, Alw26I/Eco31I/Esp3I family | met_Cyt | YES | PF00145 (HMM-CLUST): C-5 cytosine-specific DNA methylase |
Parent Properties
| Accession | Name |
|---|---|
| GenProp0116 | DNA metabolism |
| GenProp1067 | Defense systems |
Sibling Properties
| Accession | Name |
|---|---|
| GenProp0115 | DNA repair |
| GenProp0198 | ruvABC Holliday junction complex |
| GenProp0263 | DNA polymerase III, bacterial |
| GenProp0455 | restriction enzyme system, type I |
| GenProp0487 | repABC-type alpha-proteobacterial replicon(s) |
| GenProp0701 | DNA sulfur modification system dnd |
| GenProp0806 | replication initiation, bacterial |
| GenProp0977 | DNA ligase/helicase system |
| GenProp1081 | replication restart, PriA/PriB primosome pathway |
| GenProp1095 | exodeoxyribonuclease VII |
| GenProp0021 | CRISPR region |