Genome Property Definition Page
| Accession | GenProp0641 |
| Name | spermidine biosynthesis from putrescine and S-adenosylmethionine |
| Type | PATHWAY |
| Description | Spermine, spermidine and putrescine are a family of polyamines (positively charged organic polycations) that are important for cellular growth, most likely by stabilizing polynucleotides and membranes. Spermidine is derived from putrescine and the 4-aminobutyrate moiety of methionine (indirectly via S-adenosyl methionine). Spermine is synthesized by a second addition of 4-aminobutyrate to spermidine, and is more commonly found in eukaryotes. |
| JCVI Role | Polyamine biosynthesis |
| Parent Property | GenProp0063: biosynthesis |
Components
| Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
|---|---|---|---|---|
| S-adenosylmethionine decarboxylase | speD | YES | PF02675 (HMM): S-adenosylmethionine decarboxylase | |
| spermidine synthase | speE | YES | TIGR00417 (HMM): spermidine synthase |
Parent Properties
| Accession | Name |
|---|---|
| GenProp0063 | biosynthesis |
Sibling Properties
| Accession | Name |
|---|---|
| GenProp0077 | natural products biosynthesis |
| GenProp0126 | amino acid biosynthesis |
| GenProp0184 | cofactor biosynthesis |
| GenProp0185 | nucleotide biosynthesis |
| GenProp0186 | storage and structural polymer biosynthesis |
| GenProp0197 | protein biosynthesis |
| GenProp0219 | spermidine biosynthesis from arginine (via agmatine) |
| GenProp0267 | osmolyte biosynthesis |
| GenProp0642 | putrescine biosynthesis from arginine utilizing agmatinase |
| GenProp0643 | putrescine biosynthesis from arginine via ornithine |
| GenProp0644 | putrescine biosynthesis from glutamate via ornithine |
| GenProp0645 | putrescine biosynthesis |
| GenProp0724 | phosphonoacetaldehyde biosynthesis from phosphoenolpyruvate |
| GenProp0738 | agmatine to putrescine via N-carbamoylputrescine |
| GenProp0795 | carbohydrate biosynthesis |
| GenProp0838 | lipid biosynthesis |
| GenProp0909 | capreomycidine biosynthesis |
| GenProp0942 | alkane biosynthesis, cyanobacterial |
| GenProp1053 | rSAM/selenodomain system |
| GenProp1056 | rhizo-twelve system |
| GenProp1057 | radical SAM/SPASM system GeoRSP |