Genome Property Definition Page

NameA1/A0 ATPase
DescriptionThis ATP synthase is the archaebacterial version of the F1/F0 ATP synthase found in bacteria in the sense that it functions in the ATP synthetic direction [1], although it also has similarities to the V1/V0 (V-type, vacuolar) ATPase in eucarya which hydrolyzes ATP in order to acidify cellular compartments.
JCVI RoleATP-proton motive force interconversion
Parent PropertyGenProp0243: ATP synthases
Literature References
[ 1 ]Wilms R, Freiberg C, Wegerle E, Meier I, Mayer F, Muller V  Subunit structure and organization of the genes of the A1A0 ATPase from the Archaeon Methanosarcina mazei Go1.  J Biol Chem. 1996 Aug 2;271(31):18843-52.  PMID 8702544
[ 2 ]Lemker T, Gruber G, Schmid R, Muller V  Defined subcomplexes of the A1 ATPase from the archaeon Methanosarcina mazei Go1: biochemical properties and redox regulation.  FEBS Lett. 2003 Jun 5;544(1-3):206-9.  PMID 12782317
[ 3 ]Coskun U, Radermacher M, Muller V, Ruiz T, Gruber G  Three-dimensional organization of the archaeal A1-ATPase from Methanosarcina mazei Go1.  J Biol Chem. 2004 May 21;279(21):22759-64. Epub 2004 Feb 26.  PMID 14988401
[ 4 ]Muller V, Ruppert C, Lemker T  Structure and function of the A1A0-ATPases from methanogenic Archaea.  J Bioenerg Biomembr. 1999 Feb;31(1):15-27.  PMID 10340845
[ 5 ]Ruppert C, Wimmers S, Lemker T, Muller V  The A1A0 ATPase from Methanosarcina mazei: cloning of the 5' end of the aha operon encoding the membrane domain and expression of the proteolipid in a membrane-bound form in Escherichia coli.  J Bacteriol. 1998 Jul;180(13):3448-52.  PMID 9642200

Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
A1 stalk complex, A subunitAhaAYESTIGR01043 (HMM): ATP synthase archaeal, A subunit
A1 stalk complex, B subunitAhaBYESTIGR01041 (HMM): ATP synthase archaeal, B subunit
A1 stalk complex, C subunitAhaCYESTIGR02923 (HMM): ATP synthase A1, C subunit
A1 stalk complex, D subunitAhaDYESTIGR00309 (HMM): V-type ATPase, D subunit
A1 stalk complex, E subunitAhaEYESPF01991 (HMM): ATP synthase (E/31 kDa) subunit
A1 stalk complex, F subunitAhaFYESPF01990 (HMM): ATP synthase (F/14-kDa) subunit
A1 stalk complex, G subunitAhaGNO
H subunitAhaHNOTIGR02926 (HMM): ATP synthase archaeal, H subunit
A0 membrane complex, I subunitAhaINO
A0 membrane complex, K subunitAhaKNO

Parent Properties
GenProp0243ATP synthases

Sibling Properties
GenProp0128F1/F0 ATPase
GenProp0690F1F0 ATPase, Methanosarcina type