Genome Property Definition Page

Accession

GenProp0490

Name

Ti-type conjugation system

Type

SYSTEM

Description

This type IV secretion system for the exchange of plasmid DNA is found in the Agrobacterium tumefaciens Ti plasmid. This (tra/trb) system is separate from the vir system which is responsible for targetting the T-region DNA to eukaryotic host cells in the process of tumor formation.

JCVI Role

Plasmid functions

Parent Property

GenProp0076: DNA handling

Literature References

[ 1 ]Farrand SK, Hwang I, Cook DM The tra region of the nopaline-type Ti plasmid is a chimera with elements related to the transfer systems of RSF1010, RP4, and F. J Bacteriol. 1996 Jul;178(14):4233-47. PMID 8763953

Gene Ontology Term

GO:0009291: unidirectional conjugation (biological_process)

Components

Step Name	Step Num	Required	Evidence (Method)	Evidence Go Terms
Ti conjugation system relaxase TraA	TraA	YES	TIGR02768 (HMM): Ti-type conjugative transfer relaxase TraA	GO:0009291: unidirectional conjugation
Ti conjugation system protein TraB	TraB	NO	PF07186 (HMM):	GO:0009291: unidirectional conjugation
Ti conjugation system protein TraC	TraC	NO	PF07820 (HMM): TraC-like protein	GO:0009291: unidirectional conjugation
Ti conjugation system protein TraD	TraD	NO	PF06412 (HMM): conjugal transfer protein TraD	GO:0009291: unidirectional conjugation
Ti conjugation system signal peptidase TraF	TraF	NO	TIGR02771 (HMM): conjugative transfer signal peptidase TraF	GO:0009291: unidirectional conjugation
Ti conjugation system protein TraG	TraG	YES	TIGR02767 (HMM): Ti-type conjugative transfer system protein TraG	GO:0009291: unidirectional conjugation
Ti conjugation system protein TraH	TraH	NO	PF06871 (HMM): TraH_2	GO:0009291: unidirectional conjugation
Ti/vir system protein TrbB/VirB11	TrbB	NO	TIGR02782 (HMM): P-type conjugative transfer ATPase TrbB TIGR02788 (HMM): P-type DNA transfer ATPase VirB11	GO:0009291: unidirectional conjugation GO:0009291: unidirectional conjugation
Ti/vir system protein TrbF/VirB8	TrbF	YES	PF04585 (HMM): PF04335 (HMM): VirB8 protein	GO:0009291: unidirectional conjugation GO:0009291: unidirectional conjugation

Parent Properties

Accession	Name
GenProp0076	DNA handling

Sibling Properties

Accession	Name
GenProp0018	natural transformation
GenProp0056	type IV pilus
GenProp0115	DNA repair
GenProp0198	ruvABC Holliday junction complex
GenProp0311	competence-related genes
GenProp0489	F-type conjugation system
GenProp0699	DNA gyrase
GenProp0851	integration host factor
GenProp0855	integrating conjugative element, PFGI-1 class
GenProp0858	conjugative transposon, Bacteroides type