| Accession | GenProp0480 |
| Name | acetyl-CoA biosynthesis from acetate, direct |
| Type | PATHWAY |
| Description | This property's sole component is the enzyme acetyl-CoA ligase which hydrolyses ATP to AMP in the process of ligating acetate to coenzyme A. This enzyme acts essentially irreversibly in the direction of AcCoA biosynthesis and utilizes an enzyme-bound acyl-adeylate (AMP-Ac) intermediate [1]. The purpose of this property is for comparison with the various other ways of interconverting acetate and acetyl-CoA. |
| Parent Property | GenProp0479: acetate -- acetyl-CoA interconversions
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| Literature References | [ 1 ]BERG P Acyl adenylates; an enzymatic mechanism of acetate activation. J Biol Chem 1956 Oct;222(2):991-1013. PMID 13367067
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| Gene Ontology Term | GO:0019427: acetyl-CoA biosynthetic process from acetate (biological_process)
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