Accession | GenProp0476 |
Name | protein-coding palindromic elements |
Type | GUILD |
Description | Two different classes are known, so far, of mobile palindromic elements that insert in-frame into genes of certain obligate intracellular bacteria and code for an amino acid insert in the host protein. In contrast to inteins, the insert is relatively small and does not get spliced out. Rather, it appears the affected protein continues to function because the location of the insert is not destructive to correct protein folding. The two classes described so far are designated RPE, discovered in Rickettsia, and WPE, discovered in Wolbachia. |
Parent Property | GenProp0066: selfish genetic elements
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Literature References | [ 1 ]Ogata H, Suhre K, Claverie JM Discovery of protein-coding palindromic repeats in Wolbachia. Trends Microbiol 2005 Jun;13(6):253-5. PMID 15936655 [ 2 ]Ogata H, Audic S, Barbe V, Artiguenave F, Fournier PE, Raoult D, Claverie JM Selfish DNA in protein-coding genes of Rickettsia. Science 2000 Oct 13;290(5490):347-50. PMID 11030655 |
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Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
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Rickettsia palindromic element (RPE) | RPE1 | NO | TIGR01045 (HMM): rickettsial palindromic element RPE1 domain | |
Rickettsial palindromic element RPE2 domain | RPE2 | NO | TIGR03774 (HMM): rickettsial palindromic element RPE2 domain | |
Rickettsial palindromic element RPE3 domain | RPE3 | NO | TIGR03775 (HMM): rickettsial palindromic element RPE3 domain | |
Rickettsial palindromic element RPE4 domain | RPE4 | NO | TIGR03777 (HMM): rickettsial palindromic element RPE4 domain | |
Rickettsial palindromic element RPE5 domain | RPE5 | NO | TIGR03776 (HMM): rickettsial palindromic element RPE5 domain | |
Wolbachia palidromic element (WPE) | WPE | NO | TIGR02697 (HMM): Wolbachia palindromic element domain | |